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For spore inactivation, the strategy usually applied in the food industry is the intensification of traditional preservation methods to sterilization levels, which is often accompanied by decreases of nutritional and sensory properties. In order to overcome these unwanted side effects in food products, novel and emerging sterilization technologies are being developed, such as pressure\u2010assisted thermal sterilization, high\u2010pressure carbon dioxide, high\u2010pressure homogenization, and cold plasma. In this review, the application of these emergent technologies is discussed, in order to understand the effects on bacterial spores and their inactivation and thus ensure food safety of low\u2010acid foods. In general, the application of these novel technologies for inactivating spores is showing promising results. However, it is important to note that each technique has specific features that can be more suitable for a particular type of product. Thus, the most appropriate sterilization method for each product (and target microorganisms) should be assessed and carefully selected.<\/jats:p>","DOI":"10.1111\/1541-4337.12311","type":"journal-article","created":{"date-parts":[[2018,3,15]],"date-time":"2018-03-15T06:57:49Z","timestamp":1521097069000},"page":"532-555","source":"Crossref","is-referenced-by-count":56,"title":["Application of High Pressure with Homogenization, Temperature, Carbon Dioxide, and Cold Plasma for the Inactivation of Bacterial Spores: A Review"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8000-0283","authenticated-orcid":false,"given":"Rita P.","family":"Lopes","sequence":"first","affiliation":[{"name":"QOPNA, Chemistry Dept., Univ. of Aveiro Campus Univ. de Santiago  3810\u2010193 Aveiro Portugal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8593-9855","authenticated-orcid":false,"given":"Maria J.","family":"Mota","sequence":"additional","affiliation":[{"name":"QOPNA, Chemistry Dept., Univ. of Aveiro Campus Univ. de Santiago  3810\u2010193 Aveiro Portugal."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7883-2446","authenticated-orcid":false,"given":"Ana M.","family":"Gomes","sequence":"additional","affiliation":[{"name":"Escola Superior de Biotecnologia Univ. 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