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In this context, this systematic review and meta\u2010analysis, a novel approach will be presented using chemometric tools to verify and recognize patterns of antioxidant, antibacterial, and antifungal activities of EOs according to their geographic, botanical, chemical, and microbiological distribution. Scientific papers were selected following the Preferred Reporting Items for Systematic Review and Meta\u2010Analyses statement flow diagram, and the data were evaluated by the self\u2010organizing map and hierarchical cluster analysis. Overall, this novel approach allowed us to draw an overview of antioxidants and antimicrobials activities of EOs reported in 2019, through 585 articles evaluated, obtaining a dataset with more than 10,000 data, distributed in more than 80 countries, 290 plant genera, 150 chemical compounds, 30 genera of bacteria, and 10 genera of fungi. The networks for geographic, botanical, chemical, and microbiological distribution indicated that Brazil, Asia, the botanical genus\n                    <jats:italic>Thymus<\/jats:italic>\n                    , species\n                    <jats:italic>Thymus vulgaris<\/jats:italic>\n                    L. \u201cthyme,\u201d the Lamiaceae family, limonene, and the oxygenated monoterpene class were the most representative in the dataset, while the species\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    were the most used to assess the antimicrobial activity of EOs. This work can be seen as a guide for the processing of metadata using a novel approach with non\u2010conventional statistical methods. However, this preliminary approach with EOs can be extended to other sources or areas of food science.\n                  <\/jats:p>","DOI":"10.1111\/1541-4337.12773","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T09:20:45Z","timestamp":1623662445000},"page":"3136-3163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["An overview of research of essential oils by self\u2010organizing maps: A novel approach for meta\u2010analysis study"],"prefix":"10.1111","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8394-3431","authenticated-orcid":false,"given":"Diego","family":"Galvan","sequence":"first","affiliation":[{"name":"Center for Food Analysis (NAL), Technological Development Support Laboratory (LADETEC), Federal University of Rio de Janeiro (UFRJ) Cidade Universit\u00e1ria  Rio de Janeiro Brazil"},{"name":"Laboratory of Advanced Analysis in Biochemistry and 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