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This myopathy has been a persistent challenge in the poultry industry since its initial identification a decade ago. WB negatively impacts meat quality, leading to increased toughness and reduced nutritional value. Building on foundational research utilizing multiomics technologies, hypoxia\u2010induced oxidative stress has been identified as a key early event driving the pathological processes of WB. This review provides a comprehensive overview and the state\u2010of\u2010the\u2010art evidence on the pivotal role of oxidative stress in WB myopathy. It begins by examining the generation of reactive intermediates that induce oxidative damage and the host's defense mechanisms aimed at mitigating these threats. The discussion then focuses on the consequences of oxidative damage for mitochondria, protein and lipid oxidation, connective tissue remodeling, and inflammation\u2014pathological hallmarks of WB\u2010affected muscles. Additionally, the review highlights how oxidative stress influences satellite cell behavior, impairing the repair and regeneration of muscle tissues, a process implicated in WB. Finally, efforts to prevent or mitigate WB myopathy are summarized, with particular attention to potential intervention strategies targeting oxidative stress. These include innovative feed formulations and gut microbiota modulation, which show promise in alleviating the severity of the condition.<\/jats:p>","DOI":"10.1111\/1541-4337.70148","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T04:10:04Z","timestamp":1741752604000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Oxidative stress\u2010induced changes in wooden breast and mitigation strategies: A review"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0272-3002","authenticated-orcid":false,"given":"Yaqin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Food and Nutrition Sciences University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binbin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Food and Nutrition Sciences University of 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