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We systematically compiled OT data for 848 flavor compounds across 11 distinct matrices, reaffirming the decisive role of standardized measurement methodologies in ensuring data accuracy and comparability. The study reveals potential patterns in OTs and highlights their critical function in flavor science, specifically addressing current key bottlenecks in practical applications within the field. Accordingly, targeted solutions are proposed. Finally, by considering both the current state and long\u2010term requirements of odor threshold research, we outline future research directions. This review calls for increased attention from flavor researchers to this essential metric, aiming to maximize the rigor and scientific integrity of its application.<\/jats:p>","DOI":"10.1111\/1541-4337.70533","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:42:13Z","timestamp":1785393733000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Odor Thresholds in Flavor Science: A Data\u2010Driven Review From Mechanisms to Applications"],"prefix":"10.1111","volume":"25","author":[{"given":"Shiqi","family":"Yang","sequence":"first","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"},{"name":"School of Food Science and Engineering South China University of Technology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"He","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"},{"name":"School of Food Science and Engineering South China University of Technology  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silei","family":"Lv","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawen","family":"Duan","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Gao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5568-3975","authenticated-orcid":false,"given":"Hehe","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6717-9787","authenticated-orcid":false,"given":"Jinyuan","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Dong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4326-8237","authenticated-orcid":false,"given":"Baoguo","family":"Sun","sequence":"additional","affiliation":[{"name":"Key Laboratory of Geriatric Nutrition and Health, Ministry of Education Beijing Technology and Business University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1006175"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.06.032"},{"key":"e_1_2_12_4_1","unstructured":"Bingham A. 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