{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T01:31:46Z","timestamp":1792287106339,"version":"4.4.0"},"reference-count":151,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["ift.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Comp Rev Food Sci Food Safe"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Food preservation challenges have positioned packaging as a rapidly evolving, innovation\u2010driven field, with smart packaging offering transformative solutions. Among advanced materials, covalent organic frameworks (COFs) have attracted growing attention due to their permanent porosity, structural tunability, high surface area, and chemical stability. These features allow COFs to address critical needs in food packaging, including active barrier protection, antimicrobial action, and smart sensing of food freshness and spoilage. This review examines recent progress in applying COFs to food packaging, with particular focus on their ability to prolong shelf life and enable smart functionalities for real\u2010time monitoring of food quality. Safety aspects, biocompatibility, recyclability, and biodegradability are also critically evaluated, as these remain key considerations for regulatory approval and industrial translation. Although current studies report minimal cytotoxicity, long\u2010term toxicological assessments are still limited, underscoring the need for more comprehensive investigations. Looking forward, artificial intelligence (AI) and machine learning (ML) provide powerful tools for accelerating COF discovery and optimization. Their integration into COF design could streamline synthesis, improve scalability, and guide application\u2010specific material development. COFs represent a promising new class of materials poised to advance the next generation of sustainable, functional, and smart food\u2010packaging systems.<\/jats:p>","DOI":"10.1111\/1541-4337.70662","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:39:20Z","timestamp":1790678360000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Covalent Organic Frameworks in Smart Food Packaging: Advances, Challenges, and Future Prospects"],"prefix":"10.1111","volume":"25","author":[{"given":"Sara","family":"Esteghlal","sequence":"first","affiliation":[{"name":"Department of Food Science and Technology, School of Agriculture Shiraz University  Shiraz Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Daneshgar","sequence":"additional","affiliation":[{"name":"Department of Physics Sharif University of Technology  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6945-8541","authenticated-orcid":false,"given":"Navid","family":"Rabiee","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, Saveetha Dental College and Hospitals, SIMATS Saveetha University  Chennai India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6575-1401","authenticated-orcid":false,"given":"Mohammadreza","family":"Khalesi","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences University of Limerick  Limerick Ireland"},{"name":"Bernal Institute University of Limerick  Limerick Ireland"},{"name":"Health Research Institute University of Limerick  Limerick Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"issue":"6","key":"e_1_2_13_2_1","doi-asserted-by":"crossref","first-page":"5010","DOI":"10.1007\/s11947-025-03769-x","article-title":"Unlocking the Potential of Cyclodextrin\/Metal\u2013Organic Frameworks in Food Packaging Systems: An Exclusive Review on the Latest Trends","volume":"18","author":"Abedi\u2010Firoozjah R.","year":"2025","journal-title":"Food and Bioprocess Technology"},{"key":"e_1_2_13_3_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2024.103625","article-title":"Nanotechnology in Food Packaging With Implications for Sustainable Outlook and Safety Concerns","volume":"58","author":"Ahmad K.","year":"2024","journal-title":"Food Bioscience"},{"issue":"3","key":"e_1_2_13_4_1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1021\/acsmaterialslett.4c02594","article-title":"The COF Space: Materials Features, Gas Adsorption, and Separation Performances Assessed by Machine Learning","volume":"7","author":"Aksu G. 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