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Renal cortical pallor was noted on macroscopic examination in 10 of 23 cases of lethal diabetic ketoacidosis (43.5%), three of eight cases of fatal hyperglycemic nonketotic coma (37.5%), and in two of five cases of alcoholic ketoacidosis (40%). Histologic examination revealed basal vacuolization of renal tubular epithelial cells in 12 cases, <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>rmanni\u2013<jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>bstein lesions in 10, and osmotic nephrosis in three. Although renal cortical pallor did not appear to be a particularly sensitive marker for hyperglycemia or ketoacidosis, and did not correlate with the severity of these parameters, it may still represent a useful macroscopic marker for underlying metabolic conditions at autopsy and should therefore prompt measurement of vitreous humor glucose and \u03b2\u2010hydroxybutyrate levels.<\/jats:p>","DOI":"10.1111\/1556-4029.12102","type":"journal-article","created":{"date-parts":[[2013,3,14]],"date-time":"2013-03-14T06:43:06Z","timestamp":1363243386000},"page":"693-696","source":"Crossref","is-referenced-by-count":6,"title":["Renal Cortical Pallor<b>\u2014<\/b>A Useful Macroscopic Marker for Metabolic Derangements at Autopsy"],"prefix":"10.1111","volume":"58","author":[{"given":"Chong","family":"Zhou","sequence":"first","affiliation":[{"name":"School of Medical Sciences The University of Adelaide Medical School Frome Road Adelaide SA 5005 Australia"},{"name":"Forensic Science SA 21 Divett 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