{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:02:02Z","timestamp":1761102122420},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T00:00:00Z","timestamp":1423008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sickle cell trait (<jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content>) affects 300\u00a0million people globally, and awareness is growing that <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> is not an entirely benign condition; however, most reported cases have been non\u2010natural deaths. Autopsy records from the Baylor University Medical Center (<jats:styled-content style=\"fixed-case\">BUMC<\/jats:styled-content>) in Dallas, Texas, contained seven natural deaths from January 2007 to October 2013 in which micro\u2010occlusive sickling was identified at autopsy and <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> confirmed by postmortem hemoglobin fractionation. Sickle crisis was never diagnosed clinically. These cases illustrate the importance of red cell morphology in autopsy material. When sickling is suspected, hemoglobin fractionation should be performed. If confirmed, <jats:styled-content style=\"fixed-case\">SCT<\/jats:styled-content> should be listed as an autopsy finding and the severity and distribution of sickling documented. Extensive micro\u2010occlusive sickling should be considered contributory to death; however, its relative importance depends on all facts of the case. Accurate reporting should facilitate further research and the development of evidence\u2010based preventative and supportive strategies for these patients.<\/jats:p>","DOI":"10.1111\/1556-4029.12713","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T19:22:50Z","timestamp":1423077770000},"page":"807-811","source":"Crossref","is-referenced-by-count":10,"title":["Sickle Cell Trait as a Contributory Cause of Death in Natural Disease"],"prefix":"10.1111","volume":"60","author":[{"given":"Varsha","family":"Podduturi","sequence":"first","affiliation":[{"name":"Department of Pathology Baylor University Medical Center Dallas TX 75246"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph M.","family":"Guileyardo","sequence":"additional","affiliation":[{"name":"Department of Pathology Baylor University Medical Center Dallas TX 75246"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.020"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.156.7.729"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000207067"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-197912000-00038"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350390093033"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2012.1038"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.119363"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAF.0b013e318187dfcd"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1969.00300120048009"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(91)90242-H"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2005.028407"},{"issue":"6","key":"e_1_2_4_13_1","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1182\/blood.V32.6.847.847","article-title":"Physical properties of red cells as related to effects in vivo. 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Increased rigidity of erythrocytes as measured by viscosity of cells altered by chemical fixation, sickling and hypertonicity","volume":"32","author":"Ham TH","year":"1968","journal-title":"Blood"},{"key":"e_1_2_4_14_1","first-page":"1106","volume-title":"Medicolegal determination of death","author":"Perper JA","year":"2006"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2011.01774.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2006.1.48"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21247"}],"container-title":["Journal of Forensic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1556-4029.12713","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.12713","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:44:39Z","timestamp":1695516279000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1556-4029.12713"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,4]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["10.1111\/1556-4029.12713"],"URL":"https:\/\/doi.org\/10.1111\/1556-4029.12713","archive":["Portico"],"relation":{},"ISSN":["0022-1198","1556-4029"],"issn-type":[{"value":"0022-1198","type":"print"},{"value":"1556-4029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,4]]}}}