{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T07:40:39Z","timestamp":1696232439144},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,4,7]],"date-time":"2016-04-07T00:00:00Z","timestamp":1459987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A rare case of lethal idiopathic plasmacytic lymphadenopathy (<jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content>) with polyclonal hyperimmunoglobulinemia with chronic renal failure is described. A 40\u2010year\u2010old woman who had suffered from upper airways disease was admitted to the Emergency Room with acute renal failure and hypergammaglobulinemia. She developed pericardial effusion, a pruritic rash, splenomegaly and fell into a coma after 6 days. Multiple myeloma, infection, collagenopathy, and coagulopathy were ruled out. Finally, a form of malignant hypergammapathy was suspected. At autopsy, lymph nodes were infiltrated by polyclonal plasma cells and lymphocytes, with erythrophagocytosis features; immunohistochemistry confirmed the plasma cells (CD138+), with a prevalence of kappa\u2010positive cells, B (CD20+) and T (CD3+) cells. Kidneys showed advanced glomerulosclerosis containing similar infiltrates. The cause of death was <jats:styled-content style=\"fixed-case\">IPL<\/jats:styled-content> with polyclonal hypergammaglobulinemia and advanced renal failure. Similar cases are unusual, and possible medical liability associated with failure to diagnose and treat idiopathic plasmacytic lymphadenopathy deserves discussion and further studies.<\/jats:p>","DOI":"10.1111\/1556-4029.13101","type":"journal-article","created":{"date-parts":[[2016,4,10]],"date-time":"2016-04-10T17:41:15Z","timestamp":1460310075000},"page":"1139-1142","source":"Crossref","is-referenced-by-count":3,"title":["A Case of Lethal Idiopathic Plasmacytic Lymphadenopathy with Polyclonal Hypergammaglobulinemia: A Medical Challenge for the Forensic Pathologist"],"prefix":"10.1111","volume":"61","author":[{"given":"Lucia","family":"Tattoli","sequence":"first","affiliation":[{"name":"Section of Legal Medicine Department of Public Health and Pediatrics University of Turin Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Biagio","family":"Solarino","sequence":"additional","affiliation":[{"name":"Interdisciplinary Department of Medicine Institute of Legal Medicine University of Bari Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oronzo","family":"Schiraldi","sequence":"additional","affiliation":[{"name":"Internal Medicine University of Bari Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giancarlo","family":"Di Vella","sequence":"additional","affiliation":[{"name":"Section of Legal Medicine Department of Public Health and Pediatrics University of Turin Torino Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,4,7]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2007.08.001"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/106689690401200104"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyp073"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2007.11.003"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.33.237"},{"issue":"4","key":"e_1_2_4_7_1","first-page":"452","article-title":"Idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia (IPL) accompanied with severe thrombocytopenia and interstitial pneumonitis","volume":"31","author":"Tsutani H","year":"1990","journal-title":"Rinsho Ketsueki"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.549"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.31.504"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1520\/JFS14928J"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-006-0158-5"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.3960\/jslrt.53.57"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.10.040"},{"issue":"10","key":"e_1_2_4_14_1","first-page":"1133","article-title":"A case of idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia associated with chronic renal failure","volume":"32","author":"Kondo M","year":"1990","journal-title":"Nihon Jinzo Gakkai Shi"},{"issue":"2","key":"e_1_2_4_15_1","first-page":"343","article-title":"Nephropathy associated with idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia (IPL)","volume":"17","author":"Kaito K","year":"1997","journal-title":"Ryoikibetsu Shokogun Shirizu"},{"issue":"10","key":"e_1_2_4_16_1","first-page":"1196","article-title":"A case of idiopathic plasmacytic lymphadenopathy with polyclonal hyperimmunoglobulinemia associated with chronic nephritis","volume":"36","author":"Morita M","year":"1994","journal-title":"Nihon Jinzo Gakkai Shi"}],"container-title":["Journal of Forensic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1556-4029.13101","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.13101","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T18:56:23Z","timestamp":1696186583000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1556-4029.13101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,7]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/1556-4029.13101"],"URL":"https:\/\/doi.org\/10.1111\/1556-4029.13101","archive":["Portico"],"relation":{},"ISSN":["0022-1198","1556-4029"],"issn-type":[{"value":"0022-1198","type":"print"},{"value":"1556-4029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,7]]}}}