{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T05:51:59Z","timestamp":1771566719138,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T00:00:00Z","timestamp":1485302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Respiratory pathogens have been detected in forensic investigations using multiple techniques; however, no study has examined the use of automated, nested, multiplex polymerase chain reaction (<jats:styled-content style=\"fixed-case\">ANM<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content>), commonly used in living patients, in the forensic setting. This retrospective study assessed the utility of <jats:styled-content style=\"fixed-case\">ANM<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> in detecting respiratory pathogens in the pediatric forensic setting. Respiratory samples from 35 cases were tested for up to 20 respiratory pathogens. 51.4% of these cases yielded a positive <jats:styled-content style=\"fixed-case\">ANM<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> result, 20% of which were considered the cause of or contributory to death. The most commonly detected pathogens were rhinovirus\/enterovirus and respiratory syncytial virus, and these were the only pathogens determined to play a significant role in cause of death. The sampled sites and postmortem intervals tested did not affect the likelihood of a positive or negative test. <jats:styled-content style=\"fixed-case\">ANM<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> panels are effective, affordable, and rapid ancillary tools in evaluating cause of death in the forensic pediatric population.<\/jats:p>","DOI":"10.1111\/1556-4029.13415","type":"journal-article","created":{"date-parts":[[2017,1,25]],"date-time":"2017-01-25T09:33:39Z","timestamp":1485336819000},"page":"1223-1228","source":"Crossref","is-referenced-by-count":4,"title":["Use of an Automated Nested Multiplex Respiratory Pathogen <scp>PCR<\/scp> Panel Postmortem in the Pediatric Forensic Setting"],"prefix":"10.1111","volume":"62","author":[{"given":"Tiffany","family":"Baker","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Medical University of South Carolina 171 Ashley Avenue MSC 908 Charleston SC 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