{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:13:23Z","timestamp":1787314403715,"version":"build-2736575974"},"reference-count":15,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T00:00:00Z","timestamp":1553040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2019,9]]},"abstract":"Abstract<\/jats:title>\n \n Syphilis, a sexually transmitted infection caused by the bacterium\n Treponema palladium<\/jats:italic>\n , is experiencing a worldwide resurgence. The risk of syphilis infection is particularly high in men who have sex with men (\n MSM<\/jats:styled-content>\n ), especially those who are human immunodeficiency virus (\n HIV<\/jats:styled-content>\n )\u2010positive. Untreated syphilis can lead to rare but severe late\u2010stage complications, including syphilitic aortitis. Herein, we present an autopsy case of a ruptured thoracic aneurysm that resulted from an undetected case of syphilitic aortitis in an\n HIV<\/jats:styled-content>\n \u2010positive Japanese\n MSM<\/jats:styled-content>\n with undiagnosed syphilis. Although no syphilitic skin lesions were observed on the body, anatomical changes consistent with a syphilitic etiology were present at the site of the rupture, including medial aortic scarring with \u201ctree\u2010bark\u201d\u2010like atherosclerotic plaque. In addition, heart blood was positive for\n T. palladium<\/jats:italic>\n in a latex agglutination test. This case highlights for forensic pathologists the importance of recognizing syphilis as a possible underlying cause of sudden death among\n HIV<\/jats:styled-content>\n \u2010positive\n MSM<\/jats:styled-content>\n .\n <\/jats:p>","DOI":"10.1111\/1556-4029.14046","type":"journal-article","created":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T12:49:28Z","timestamp":1553086168000},"page":"1555-1558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Ruptured Syphilitic Aneurysm: A Cause of Sudden Death in a Man with Human Immunodeficiency Coinfection"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3746-7902","authenticated-orcid":false,"given":"Ayako","family":"Ro","sequence":"first","affiliation":[{"name":"Department of Legal Medicine St. Marianna University School of Medicine Kanagawa 216\u20108511 Japan"},{"name":"Tokyo Medical Examiner's Office Otuska 4\u201021\u201018, Bunkyo\u2010ku Tokyo 112\u20100012 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinjirou","family":"Mori","sequence":"additional","affiliation":[{"name":"Tokyo Medical Examiner's Office Otuska 4\u201021\u201018, Bunkyo\u2010ku Tokyo 112\u20100012 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimasa","family":"Kageyama","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine St. Marianna University School of Medicine Kanagawa 216\u20108511 Japan"},{"name":"Tokyo Medical Examiner's Office Otuska 4\u201021\u201018, Bunkyo\u2010ku Tokyo 112\u20100012 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shoetsu","family":"Chiba","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine St. Marianna University School of Medicine Kanagawa 216\u20108511 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiji","family":"Mukai","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine St. Marianna University School of Medicine Kanagawa 216\u20108511 Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,20]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2013.08.005"},{"key":"e_1_2_5_3_1","unstructured":"Centers for Disease Control and Prevention.Sexually transmitted diseases surveillance 2017;https:\/\/www.cdc.gov\/std\/stats17\/syphilis.htm(accessed February 22 2019)."},{"issue":"2","key":"e_1_2_5_4_1","first-page":"85","article-title":"Effect of HIV infection on the course of syphilis","volume":"10","author":"Pialoux G","year":"2008","journal-title":"AIDS Rev"},{"issue":"4","key":"e_1_2_5_5_1","first-page":"361","article-title":"Cardiovascular syphilis in HIV infection: a case\u2010control 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pallidum","volume":"39","author":"Matsumoto M","year":"1993","journal-title":"Clin Chem"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0379-0738(84)90151-8"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10561-011-9252-6"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12024-011-9266-1"}],"container-title":["Journal of Forensic 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