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As each tooth region is known to have different correlations with CA, this study aimed to segment and quantify the sectional volumes of the tooth crown and root from CBCT scans to test their correlations with the chronological age (CA). Seventy\u2010five CBCT scans from individuals with age between 20 and 60\u2009years were collected retrospectively from an existing database. A total of 192 intact maxillary anterior teeth fulfilled the eligibility criteria. The upper tooth volume ratio (UTVR), lower tooth volume ratio (LTVR), and sex were used as predictor variables. The UTVR and LTVR parameters were both found to be differently correlated to CA and independent from each other. Regression models were derived from each tooth, with the highest <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> being the maxillary lateral incisor (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.67). Additional single predictor models using each ratio were capable of reliably predicting the CA. The segmentation approach in volumetric adult dental age estimation proved to be beneficial in enhancing the reliability of the regression model.<\/jats:p>","DOI":"10.1111\/1556-4029.15094","type":"journal-article","created":{"date-parts":[[2022,7,12]],"date-time":"2022-07-12T11:30:08Z","timestamp":1657625408000},"page":"1890-1898","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Regressive changes of crown\u2010root morphology and their volumetric segmentation for adult dental age estimation"],"prefix":"10.1111","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5045-6773","authenticated-orcid":false,"given":"Rizky","family":"Merdietio Boedi","sequence":"first","affiliation":[{"name":"Centre of Forensic and Legal Medicine and Dentistry University of Dundee  Dundee UK"},{"name":"Department of Dentistry, Faculty of Medicine Universitas Diponegoro  Semarang Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Shepherd","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dentistry University of Dundee  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8838-6635","authenticated-orcid":false,"given":"Fahmi","family":"Oscandar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology \u2010 Forensic Odontology, Faculty of Dentistry Universitas Padjadjaran  Bandung Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8352-2888","authenticated-orcid":false,"given":"Scheila","family":"M\u00e2nica","sequence":"additional","affiliation":[{"name":"Centre of Forensic and Legal Medicine and Dentistry University of Dundee  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1417-2781","authenticated-orcid":false,"given":"Ademir","family":"Franco","sequence":"additional","affiliation":[{"name":"Centre of Forensic and Legal Medicine and Dentistry University of Dundee  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2009.09.008"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4800972"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11547\u2010015\u20100521\u20105"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1556\u20104029.12351"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1950.0132"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0015\u20107368(62)70094\u20100"},{"issue":"21","key":"e_1_2_8_8_1","first-page":"40","article-title":"Age determination in human teeth","volume":"22","author":"Johanson G","year":"1971","journal-title":"Odontol Revy"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1520\/JFS10735J"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0379\u20100738(93)90152\u2010z"},{"issue":"1","key":"e_1_2_8_11_1","first-page":"6","article-title":"A non\u2010destructive dental method for age estimation","volume":"12","author":"Kvaal S","year":"1994","journal-title":"J Forensic Odontostomatol"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00414\u2010010\u20100488\u20107"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.18311\/jfds\/12\/1\/2020.4"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2006.02.031"},{"issue":"2","key":"e_1_2_8_15_1","first-page":"35","article-title":"Reliability and repeatability of pulp volume reconstruction through three different volume calculations","volume":"34","author":"Penaloza TYM","year":"2016","journal-title":"J Forensic Odontostomatol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20210335"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/00450618.2021.1882567"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100722.1992.tb01740.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.1330680105"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3758\/brm.41.4.1149"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00031305.1982.10482818"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ress.2015.05.018"},{"key":"e_1_2_8_23_1","unstructured":"GamerM LemonJ GamerMM RobinsonA Kendall'sW.Various coefficients of interrater reliability and agreement.2012[updated 2021 Dec 21]. 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