{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:41:45Z","timestamp":1787013705491,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T00:00:00Z","timestamp":1717891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T00:00:00Z","timestamp":1717891200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Novel psychoactive substances (NPS) are everchanging and plague forensic laboratories who must identify an unending variety of emerging substances and evolve current methodologies to detect these substances. Identifying potential regional NPS targets and timely examining trends in seized drug data could help mitigate the burden laboratories face. Over 17\u2009months, NPS seized drug data were processed and categorized from three laboratories located across the United States to determine any NPS regional similarities and prevalent NPS drug categories: the South Carolina Law Enforcement Division (SLED), the Sedgwick County Regional Forensic Science Center (SCRFSC), and the Orange County Crime Laboratory (OCCL). Seized drug materials, including pills, powders, and plant material, were primarily analyzed for NPS via gas chromatography\u2013mass spectrometry and Fourier transform infrared spectroscopy. From June 2022 to October 2023, 1940 NPS seized drug identifications were reported by these laboratories with 63 different NPS reported. Novel synthetic opioids (NSO) were the most prevalent NPS class across all three laboratories (55%), with fluorofentanyl accounting for 74% of NSO identifications. This is unsurprising given the fentanyl epidemic in the United States. Furthermore, these data highlighted varying regional NPS seized drug trends: eutylone, a synthetic cathinone, was one of the most frequently identified NPS in SLED, SCRFSC observed the most diverse set of synthetic cannabinoids, and OCCL observed an increased prevalence in the designer benzodiazepine, bromazolam. NPS scope recommendations are a valuable resource for forensic laboratories; however, most focus on a national perspective. Timely analysis and reporting of NPS seized drug data may help to develop regional NPS scope recommendations laboratories may employ.<\/jats:p>","DOI":"10.1111\/1556-4029.15556","type":"journal-article","created":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T00:38:49Z","timestamp":1717979929000},"page":"1392-1399","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Seized drug reporting of\n                    <scp>NPS<\/scp>\n                    helps to guide regional toxicological practice: A 17\u2009month review between 2022 and 2023"],"prefix":"10.1111","volume":"69","author":[{"given":"Kayla N.","family":"Ellefsen","sequence":"first","affiliation":[{"name":"Travis County Medical Examiner  Austin Texas USA"},{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna M.","family":"Papsun","sequence":"additional","affiliation":[{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"},{"name":"NMS Labs  Horsham Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dani C.","family":"Mata","sequence":"additional","affiliation":[{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"},{"name":"Orange County Crime Lab  Santa Ana California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L.","family":"Ayala","sequence":"additional","affiliation":[{"name":"Houston Forensic Science Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celia","family":"Modell","sequence":"additional","affiliation":[{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"},{"name":"South Carolina Law Enforcement Division  Columbia South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lana J.","family":"Goodson","sequence":"additional","affiliation":[{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"},{"name":"Sedgwick County Regional Forensic Science Center  Wichita Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3747-5379","authenticated-orcid":false,"given":"Michael T.","family":"Truver","sequence":"additional","affiliation":[{"name":"Society of Forensic Toxicologists Novel Psychoactive Substances Committee  Mesa Arizona USA"},{"name":"Department of Pathology, Immunology, and Laboratory Medicine University of Florida College of Medicine  Gainesville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,9]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"European Monitoring Centre for Drugs and Drug Addiction. European drug report 2023.New psychoactive substances\u2013the current situation in Europe (European Drug Report 2023).2023Accessed 6 February 2024.https:\/\/www.emcdda.europa.eu\/sites\/default\/files\/pdf\/31091_en.pdf?716988"},{"key":"e_1_2_8_3_1","article-title":"Understanding the synthetic drug market","volume":"19","author":"United Nations Office on Drugs and Crime (UNODC)","year":"2019","journal-title":"The NPS Factor Global Smart Update"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2021.110918"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2021.103393"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2021.116891"},{"key":"e_1_2_8_7_1","unstructured":"The Center of Forensic Science Research & Education.Scope Recommendations. Accessed 18 December 2023.https:\/\/www.cfsre.org\/nps\u2010discovery\/scope\u2010recommendations"},{"key":"e_1_2_8_8_1","article-title":"UNODC early warning advisory on new psychoactive substances","author":"UNODC","journal-title":"What Are NPS?"},{"issue":"4","key":"e_1_2_8_9_1","first-page":"25","article-title":"Keeping up: a 12\u2010month look into NPS seized drug trends","volume":"47","author":"Ellefsen KN","year":"2023","journal-title":"ToxTalk"},{"key":"e_1_2_8_10_1","volume-title":"NFLIS\u2010drug brief: substances co\u2010reported with fentanyl in NFLIS\u2010drug and DEA\u2010Tox, January 2013\u2013June 2023","author":"Diversion Control Division","year":"2023"},{"key":"e_1_2_8_11_1","unstructured":"The Center of Forensic Science Research & Education.Q3 drug checking quarterly report\u2013Philadelphia PA.2022Accessed 14 August 2023.https:\/\/www.cfsre.org\/images\/content\/reports\/drug_checking\/2022_Q3_Drug_Checking_Quarterly_Report_Philadelphia.pdf"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkac049"},{"key":"e_1_2_8_13_1","volume-title":"National Forensic Laboratory Information System","author":"Diversion Control Division","year":"2023"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.40736"},{"key":"e_1_2_8_15_1","unstructured":"The Center of Forensic Science Research & Education.NPS opioids in the United States\u2013Trend report\u2013Q3.2023Accessed 18 December 2023.https:\/\/www.cfsre.org\/nps\u2010discovery\/trend\u2010reports\/nps\u2010opioids\/report\/49?trend_type_id=2"},{"key":"e_1_2_8_16_1","unstructured":"The Center of Forensic Science Research & Education.NPS stimulants and hallucinogens in the United States\u2013Trend report\u2013Q2.2023Accessed 11 Aug 2023.https:\/\/www.cfsre.org\/nps\u2010discovery\/trend\u2010reports\/nps\u2010stimulants\u2010and\u2010hallucinogens\/report\/49?trend_type_id=3"},{"key":"e_1_2_8_17_1","unstructured":"The Center of Forensic Science Research & Education.NPS benzodiazepines in the United States\u2013Trend report\u2013Q2.2023Accessed 11 August 2023.https:\/\/www.cfsre.org\/nps\u2010discovery\/trend\u2010reports\/nps\u2010benzodiazepines\/report\/49?trend_type_id=1"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkad037"},{"key":"e_1_2_8_19_1","unstructured":"The Center of Forensic Science Research & Education.Synthetic cannabinoids in the United States\u2013Trend report\u2013Q2 2023. Accessed 11 August 2023.https:\/\/www.cfsre.org\/nps\u2010discovery\/trend\u2010reports\/synthetic\u2010cannabinoids\/report\/49?trend_type_id=4"}],"container-title":["Journal of Forensic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.15556","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1556-4029.15556","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.15556","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T15:03:39Z","timestamp":1772982219000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1556-4029.15556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,9]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/1556-4029.15556"],"URL":"https:\/\/doi.org\/10.1111\/1556-4029.15556","archive":["Portico"],"relation":{},"ISSN":["0022-1198","1556-4029"],"issn-type":[{"value":"0022-1198","type":"print"},{"value":"1556-4029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,9]]},"assertion":[{"value":"2024-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}