{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:41:47Z","timestamp":1787013707228,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Xylazine, an \u03b1\n                    <jats:sub>2<\/jats:sub>\n                    \u2010adrenergic receptor agonist commonly used as a veterinary sedative, has gained notoriety for its increasing misuse in combination with opioids, such as fentanyl, to potentiate its effects. This trend has led to a rise in cases of xylazine poisoning. Although timely diagnosis and intervention have reduced fatalities, the postmortem pathological manifestations and lethal blood concentration of xylazine alone remain poorly characterized due to its common co\u2010occurrence in toxicology with fentanyl. This study presented a case of homicide involving fatal intoxication solely from xylazine overdose without coadministration of other central nervous system drugs, detailing the multi\u2010organ pathological changes observed and quantifying the decedent's blood xylazine concentration at 13.34\u2009\u03bcg\/mL using liquid chromatography\u2010tandem mass spectrometry (LC\u2013MS\/MS). The findings aimed to provide forensic practitioners with valuable insights for the identification and investigation of fatal xylazine poisoning cases.\n                  <\/jats:p>","DOI":"10.1111\/1556-4029.70104","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T00:14:15Z","timestamp":1749773655000},"page":"2102-2107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Forensic pathology and toxicological analyses: A case of fatal xylazine poisoning"],"prefix":"10.1111","volume":"70","author":[{"given":"Zhonghao","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangting","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erjuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Hubei Chongxin Forensic Center  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghong","family":"Ma","sequence":"additional","affiliation":[{"name":"Hubei Chongxin Forensic Center  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwu","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2014.03.015"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2023.104154"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2022.2063135"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jflm.2024.102780"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkac049"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2023.2288540"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2015.09.051"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics11121012"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010023\u201006390\u2010y"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0236594"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/37124"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2021.03.033"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.70101"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/acb385723"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2015.06.005"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/bkae009"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2024.124059"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/1556\u20104029.13684"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2024.119826"}],"container-title":["Journal of Forensic Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.70104","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1556-4029.70104","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1556-4029.70104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T05:26:19Z","timestamp":1776057979000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1556-4029.70104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,12]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["10.1111\/1556-4029.70104"],"URL":"https:\/\/doi.org\/10.1111\/1556-4029.70104","archive":["Portico"],"relation":{},"ISSN":["0022-1198","1556-4029"],"issn-type":[{"value":"0022-1198","type":"print"},{"value":"1556-4029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,12]]},"assertion":[{"value":"2025-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}