{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T07:12:51Z","timestamp":1777965171354,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Forensic Sciences"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Determining fatal insulin overdose remains a major challenge in forensic practice due to the absence of characteristic histopathological findings and technical limitations in postmortem insulin detection. This report presented a complex case of a 69\u2010year\u2010old diabetic female involved in a suicide pact with her son, who was subjected to estazolam ingestion, excessive insulin injection, and a sharp\u2010force incised wound of the left wrist with transection of the radial artery. She survived for more than 48\u2009h after drug administration before ultimately succumbing to fatal sharp\u2010force trauma inflicted by her son. Immunohistochemical staining confirmed insulin deposition at injection sites, and radioimmunoassay revealed markedly elevated insulin levels accompanied by a suppressed C\u2010peptide concentration\u2014findings consistent with exogenous insulin administration. Liquid chromatography\u2013tandem mass spectrometry (LC\u2013MS\/MS) detected estazolam at a concentration of 18.2\u2009ng\/mL in blood. Forensic evidence confirmed the son's direct involvement at the scene. Based on the totality of the evidence, it was definitively concluded that the injuries were homicidal. This study offered valuable insights for the forensic identification and investigation of complex insulin\u2010related fatalities.<\/jats:p>","DOI":"10.1111\/1556-4029.70299","type":"journal-article","created":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T04:31:51Z","timestamp":1775104311000},"page":"1535-1541","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Suicidal insulin injection combined with homicidal wrist incision"],"prefix":"10.1111","volume":"71","author":[{"given":"Xiangting","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Forensic Medicine Tongji Medical College, Huazhong University of Science and Technology  Wuhan People's Republic of China"},{"name":"First Affiliated Hospital, Shihezi University\/Department of Pathology and key Laboratory for Xinjiang Endemic and Ethnic Diseases, Shihezi University School of Medicine  Shihezi People's Republic of 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