{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T02:41:06Z","timestamp":1789094466792,"version":"build-2803163510"},"reference-count":26,"publisher":"Oxford University Press (OUP)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEMS Yeast Res"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1111\/1567-1364.12193","type":"journal-article","created":{"date-parts":[[2014,8,5]],"date-time":"2014-08-05T14:03:52Z","timestamp":1407247432000},"page":"n\/a-n\/a","source":"Crossref","is-referenced-by-count":12,"title":["Environmental azole fungicide, prochloraz, can induce cross-resistance to medical triazoles in<i>Candida glabrata<\/i>"],"prefix":"10.1093","author":[{"given":"Isabel","family":"Faria-Ramos","sequence":"first","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro R.","family":"Tavares","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Farinha","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Neves-Maia","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel M.","family":"Miranda","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"Cardiovascular Research & Development Unit; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"CINTESIS - Center for Health Technology and Services Research; Faculty of Medicine; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel M.","family":"Silva","sequence":"additional","affiliation":[{"name":"IPATIMUP-Institute of Molecular Pathology and Immunology; University of Porto; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia M.","family":"Estevinho","sequence":"additional","affiliation":[{"name":"CIMO-Mountain Research Center; Department of Biology and Biotechnology; Agricultural College of Bragan\u00e7a; Polytechnic Institute of Bragan\u00e7a; Bragan\u00e7a Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cidalia","family":"Pina-Vaz","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"Cardiovascular Research & Development Unit; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"CINTESIS - Center for Health Technology and Services Research; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"Clinical Pathology; Centro Hospitalar de S\u00e3o Jo\u00e3o; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ac\u00e1cio G.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"Cardiovascular Research & Development Unit; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"CINTESIS - Center for Health Technology and Services Research; Faculty of Medicine; University of Porto; Porto Portugal"},{"name":"Burn Unit; Centro Hospitalar de S\u00e3o Jo\u00e3o; Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2014,8,28]]},"reference":[{"key":"10.1111\/1567-1364.12193-BIB0001|fyr12193-cit-0001","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1128\/AAC.48.5.1773-1777.2004","article-title":"Mechanism of increased fluconazole resistance in Candida glabrata during prophylaxis","volume":"48","author":"Bennett","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0002|fyr12193-cit-0002","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1128\/AAC.49.2.783-787.2005","article-title":"Rapid acquisition of stable azole resistance by Candida glabrata isolates obtained before the clinical introduction of fluconazole","volume":"49","author":"Borst","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0003|fyr12193-cit-0003","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/ps.3567","article-title":"Environmental fungicides and triazole resistance in Aspergillus","volume":"70","author":"Bowyer","year":"2014","journal-title":"Pest Manag Sci"},{"key":"10.1111\/1567-1364.12193-BIB0004|fyr12193-cit-0004","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1128\/IAI.71.12.7109-7118.2003","article-title":"Phenotypic switching and mating type switching of Candida glabrata at sites of colonization","volume":"71","author":"Brockert","year":"2003","journal-title":"Infect Immun"},{"key":"10.1111\/1567-1364.12193-BIB0005|fyr12193-cit-0005","unstructured":"Clinical and Laboratory Standards Institute Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Fourth Informational Supplement 2012"},{"key":"10.1111\/1567-1364.12193-BIB0006|fyr12193-cit-0006","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s10096-007-0448-4","article-title":"A first Portuguese epidemiological survey of fungemia in a university hospital","volume":"27","author":"Costa-de-Oliveira","year":"2008","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1111\/1567-1364.12193-BIB0007|fyr12193-cit-0007","doi-asserted-by":"crossref","first-page":"e1000268","DOI":"10.1371\/journal.ppat.1000268","article-title":"Gain of function mutations in CgPDR1 of Candida glabrata not only mediate antifungal resistance but also enhance virulence","volume":"5","author":"Ferrari","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1111\/1567-1364.12193-BIB0008|fyr12193-cit-0008","doi-asserted-by":"crossref","first-page":"2987","DOI":"10.1128\/AAC.45.11.2987-2990.2001","article-title":"Critical annotations to the use of azole antifungals for plant protection","volume":"45","author":"Hof","year":"2001","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0009|fyr12193-cit-0009","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.drup.2008.01.001","article-title":"Is there a serious risk of resistance development to azoles among fungi due to the widespread use and long-term application of azole antifungals in medicine?","volume":"11","author":"Hof","year":"2008","journal-title":"Drug Resist Updat"},{"key":"10.1111\/1567-1364.12193-BIB0010|fyr12193-cit-0010","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1086\/524071","article-title":"Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact","volume":"46","author":"Kanafani","year":"2008","journal-title":"Clin Infect Dis"},{"key":"10.1111\/1567-1364.12193-BIB0011|fyr12193-cit-0011","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/0076-6879(91)94030-G","article-title":"Preparation of high molecular weight RNA","volume":"194","author":"K\u00f6hrer","year":"1991","journal-title":"Methods Enzymol"},{"key":"10.1111\/1567-1364.12193-BIB0012|fyr12193-cit-0012","doi-asserted-by":"crossref","first-page":"3014","DOI":"10.1128\/AAC.00459-07","article-title":"Cross-resistance to medical and agricultural azole drugs in yeasts from the oropharynx of human immunodeficiency virus patients and from environmental Bavarian vine grapes","volume":"51","author":"M\u00fcller","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0013|fyr12193-cit-0013","first-page":"68","volume-title":"Ecology and Epidemiology of Candidiasis. Candida and Candidosis","author":"Odds","year":"1988"},{"key":"10.1111\/1567-1364.12193-BIB0014|fyr12193-cit-0014","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1470-9465.2004.t01-1-00844.x","article-title":"Twelve years of fluconazole in clinical practice: global trends in species distribution and fluconazole susceptibility of bloodstream isolates of Candida","volume":"10","author":"Pfaller","year":"2004","journal-title":"Clin Microbiol Infect"},{"key":"10.1111\/1567-1364.12193-BIB0015|fyr12193-cit-0015","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1128\/CMR.00029-06","article-title":"Epidemiology of invasive candidiasis: a persistent public health problem","volume":"20","author":"Pfaller","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"10.1111\/1567-1364.12193-BIB0016|fyr12193-cit-0016","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1128\/JCM.41.5.2176-2179.2003","article-title":"Variation in susceptibility of bloodstream isolates of Candida glabrata to fluconazole according to patient age and geographic location","volume":"41","author":"Pfaller","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1111\/1567-1364.12193-BIB0017|fyr12193-cit-0017","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.diagmicrobio.2003.09.008","article-title":"In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program","volume":"48","author":"Pfaller","year":"2004","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1111\/1567-1364.12193-BIB0018|fyr12193-cit-0018","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1111\/j.1567-1364.2009.00508.x","article-title":"Dynamics of in vitro acquisition of resistance by Candida parapsilosis to different azoles","volume":"9","author":"Pinto e Silva","year":"2009","journal-title":"FEMS Yeast Res"},{"key":"10.1111\/1567-1364.12193-BIB0019|fyr12193-cit-0019","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1128\/AAC.49.2.668-679.2005","article-title":"Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance","volume":"49","author":"Sanguinetti","year":"2005","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0020|fyr12193-cit-0020","doi-asserted-by":"crossref","first-page":"3672","DOI":"10.1128\/AAC.00654-07","article-title":"Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy","volume":"51","author":"Serfling","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0021|fyr12193-cit-0021","doi-asserted-by":"crossref","first-page":"4053","DOI":"10.1128\/AEM.00231-09","article-title":"Possible environmental origin of resistance of Aspergillus fumigatus to medical triazoles","volume":"75","author":"Snelders","year":"2009","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/1567-1364.12193-BIB0022|fyr12193-cit-0022","doi-asserted-by":"crossref","first-page":"e31801","DOI":"10.1371\/journal.pone.0031801","article-title":"Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus","volume":"7","author":"Snelders","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/1567-1364.12193-BIB0023|fyr12193-cit-0023","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s15010-013-0455-6","article-title":"A 1-year prospective survey of candidemia in Italy and changing epidemiology over one decade","volume":"41","author":"Tortorano","year":"2013","journal-title":"J Infect"},{"key":"10.1111\/1567-1364.12193-BIB0024|fyr12193-cit-0024","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1128\/AAC.50.4.1384-1392.2006","article-title":"Candida glabrata PDR1, a transcriptional regulator of a pleiotropic drug resistance network, mediates azole resistance in clinical isolates and petite mutants","volume":"50","author":"Tsai","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1111\/1567-1364.12193-BIB0025|fyr12193-cit-0025","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1111\/j.1365-2958.2006.05235.x","article-title":"Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies","volume":"61","author":"Vermitsky","year":"2006","journal-title":"Mol Microbiol"},{"key":"10.1111\/1567-1364.12193-BIB0026|fyr12193-cit-0026","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S1473-3099(09)70265-8","article-title":"Azole resistance in Aspergillus fumigatus: a side-effect of environmental fungicide use?","volume":"9","author":"Verweij","year":"2009","journal-title":"Lancet Infect Dis"}],"container-title":["FEMS Yeast Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femsyr\/article-pdf\/14\/7\/1119\/18776805\/14-7-1119.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T07:59:25Z","timestamp":1503475165000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsyr\/article-lookup\/doi\/10.1111\/1567-1364.12193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":26,"URL":"https:\/\/doi.org\/10.1111\/1567-1364.12193","relation":{},"ISSN":["1567-1356"],"issn-type":[{"value":"1567-1356","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}