{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:23:14Z","timestamp":1790414594424,"version":"4.1.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FEMS Microbiol Lett"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1111\/1574-6968.12107","type":"journal-article","created":{"date-parts":[[2013,2,18]],"date-time":"2013-02-18T22:45:57Z","timestamp":1361227557000},"page":"45-53","source":"Crossref","is-referenced-by-count":14,"title":["Generation and analysis of an ICE R391 deletion library identifies genes involved in the element encoded UV-inducible cell-sensitising function"],"prefix":"10.1093","volume":"342","author":[{"given":"Patricia","family":"Armshaw","sequence":"first","affiliation":[{"name":"Department of Chemical and Environmental Sciences; Molecular and Structural Biochemistry Laboratory; University of Limerick; Limerick; Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Tony","family":"Pembroke","sequence":"additional","affiliation":[{"name":"Department of Chemical and Environmental Sciences; Molecular and Structural Biochemistry Laboratory; University of Limerick; Limerick; Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2013,3,7]]},"reference":[{"key":"10.1111\/1574-6968.12107-BIB0001|fml12107-cit-0001","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1128\/MMBR.00023-09","article-title":"Biological diversity of prokaryotic type IV secretion systems","volume":"73","author":"Alvarez-Martinez","year":"2009","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1111\/1574-6968.12107-BIB0003|fml12107-cit-0003","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.1128\/JB.184.15.4259-4269.2002","article-title":"Genomic and functional analyses of SXT, an integrating antibiotic resistance gene transfer element derived from Vibrio cholerae","volume":"184","author":"Beaber","year":"2002","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0004|fml12107-cit-0004","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/nature02241","article-title":"SOS response promotes horizontal dissemination of antibiotic resistance genes","volume":"427","author":"Beaber","year":"2004","journal-title":"Nature"},{"key":"10.1111\/1574-6968.12107-BIB0005|fml12107-cit-0005","doi-asserted-by":"crossref","first-page":"D621","DOI":"10.1093\/nar\/gkr846","article-title":"ICEberg: a web-based resource for integrative and conjugative elements found in Bacteria","volume":"40","author":"Bi","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"10.1111\/1574-6968.12107-BIB0006|fml12107-cit-0006","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1128\/JB.184.18.5158-5169.2002","article-title":"R391: a conjugative integrating mosaic comprised of phage, plasmid, and transposon elements","volume":"184","author":"Boltner","year":"2002","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0007|fml12107-cit-0007","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1462-2920.2009.02094.x","article-title":"Beyond antibiotic resistance: integrating conjugative elements of the SXT\/R391 family that encode novel diguanylate cyclases participate to c-di-GMP signalling in Vibrio cholerae","volume":"12","author":"Bordeleau","year":"2010","journal-title":"Environ Microbiol"},{"key":"10.1111\/1574-6968.12107-BIB0008|fml12107-cit-0008","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.plasmid.2006.01.001","article-title":"The current ICE age: biology and evolution of SXT-related integrating conjugative elements","volume":"55","author":"Burrus","year":"2006","journal-title":"Plasmid"},{"key":"10.1111\/1574-6968.12107-BIB0009|fml12107-cit-0009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/28.22.e97","article-title":"A rapid method for efficient gene replacement in the filamentous fungus Aspergillus nidulans","volume":"28","author":"Chaveroche","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"10.1111\/1574-6968.12107-BIB0010|fml12107-cit-0010","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1471-2199-12-16","article-title":"Functional characterization of an alkaline exonuclease and single strand annealing protein from the SXT genetic element of Vibrio cholerae","volume":"12","author":"Chen","year":"2011","journal-title":"BMC Mol Biol"},{"key":"10.1111\/1574-6968.12107-BIB0011|fml12107-cit-0011","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1111\/j.1365-2958.2010.07364.x","article-title":"Integrating conjugative elements of the SXT\/R391 family trigger the excision and drive the mobilization of a new class of Vibrio genomic islands","volume":"78","author":"Daccord","year":"2010","journal-title":"Mol Microbiol"},{"key":"10.1111\/1574-6968.12107-BIB0012|fml12107-cit-0012","doi-asserted-by":"crossref","first-page":"6640","DOI":"10.1073\/pnas.120163297","article-title":"One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products","volume":"97","author":"Datsenko","year":"2000","journal-title":"P Natl Acad Sci USA"},{"key":"10.1111\/1574-6968.12107-BIB0013|fml12107-cit-0013","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1126\/science.1166101","article-title":"Structure of a type IV secretion system core complex","volume":"323","author":"Fronzes","year":"2009","journal-title":"Science"},{"key":"10.1111\/1574-6968.12107-BIB0014|fml12107-cit-0014","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1128\/JB.164.3.1238-1247.1985","article-title":"Characterisation and sequence analysis of pilin from F-like plasmids","volume":"164","author":"Frost","year":"1985","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0015|fml12107-cit-0015","doi-asserted-by":"crossref","first-page":"4121","DOI":"10.1128\/jb.177.14.4121-4130.1995","article-title":"Tight regulation, modulation, and high-level expression by vectors containing the arabinose pBAD promoter","volume":"177","author":"Guzman","year":"1995","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0016|fml12107-cit-0016","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1128\/JB.184.11.3126-3129.2002","article-title":"Roles of internal cysteines in the function, localisation, and reactivity of the TraV outer membrane lipoprotein encoded by the F plasmid","volume":"184","author":"Harris","year":"2002","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0018|fml12107-cit-0018","doi-asserted-by":"crossref","first-page":"2737","DOI":"10.1128\/jb.177.10.2737-2743.1995","article-title":"Characterization of the umu-complementing operon from R391","volume":"177","author":"Kulaeva","year":"1995","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0019|fml12107-cit-0019","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1128\/jb.172.2.741-747.1990","article-title":"Transcriptional analysis of the flagellar regulon of Salmonella typhimurium","volume":"172","author":"Kutsukake","year":"1990","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0020|fml12107-cit-0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1097(03)00430-0","article-title":"F factor conjugation is a true type IV secretion system","volume":"224","author":"Lawley","year":"2003","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/1574-6968.12107-BIB0021|fml12107-cit-0021","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.devcel.2005.05.004","article-title":"Interactions between inner membrane proteins in donor and recipient cells limit conjugal DNA transfer","volume":"8","author":"Marrero","year":"2005","journal-title":"Dev Cell"},{"key":"10.1111\/1574-6968.12107-BIB0022|fml12107-cit-0022","doi-asserted-by":"crossref","first-page":"3302","DOI":"10.1128\/JB.01902-06","article-title":"The SXT\/R391 family of integrative conjugative elements is composed of two exclusion groups","volume":"189","author":"Marrero","year":"2007a","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0023|fml12107-cit-0023","doi-asserted-by":"crossref","first-page":"6469","DOI":"10.1128\/JB.00522-07","article-title":"Determinants of entry exclusion within Eex and TraG are cytoplasmic","volume":"189","author":"Marrero","year":"2007b","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0024|fml12107-cit-0024","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1093\/jac\/dkr286","article-title":"Prevalence of SXT\/R391-like integrative and conjugative elements carrying bla(CMY-2) in Proteus mirabilis","volume":"66","author":"Mata","year":"2011","journal-title":"J Antimicrob Chemother"},{"key":"10.1111\/1574-6968.12107-BIB0025|fml12107-cit-0025","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1574-6968.2004.tb09673.x","article-title":"Detailed analysis of the insertion site of the mobile elements R997, pMERPH, R392, R705 and R391 in E.\u00a0coli K12","volume":"237","author":"McGrath","year":"2004","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/1574-6968.12107-BIB0026|fml12107-cit-0026","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.femsle.2005.01.013","article-title":"Pre-exposure to UV irradiation increases the transfer frequency of the IncJ conjugative transposon-like elements R391, R392, R705, R706 R997 and pMERPH and is recA(+) dependent","volume":"243","author":"McGrath","year":"2005","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/1574-6968.12107-BIB0027|fml12107-cit-0027","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.mimet.2005.10.004","article-title":"Molecular tools to detect the IncJ elements: a family of integrating, antibiotic resistant mobile genetic elements","volume":"66","author":"McGrath","year":"2006","journal-title":"J Microbiol Meth"},{"key":"10.1111\/1574-6968.12107-BIB0028|fml12107-cit-0028","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1111\/j.1365-2958.2006.05561.x","article-title":"Characterization of polVR391: a Y-family polymerase encoded by rumA'B from the IncJ conjugative transposon, R391","volume":"63","author":"Mead","year":"2007","journal-title":"Mol Microbiol"},{"key":"10.1111\/1574-6968.12107-BIB0029|fml12107-cit-0029","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/JB.180.8.2063-2071.1998","article-title":"Use of bacteriophage lambda recombination functions to promote gene replacement in Escherichia coli","volume":"180","author":"Murphy","year":"1998","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0030|fml12107-cit-0030","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1574-6968.2007.00747.x","article-title":"The orf4 gene of the enterobacterial ICE, R391, encodes a novel UV-inducible recombination directionality factor, Jef, involved in excision and transfer of the ICE","volume":"272","author":"O'Halloran","year":"2007","journal-title":"FEMS Microbiol Lett"},{"key":"10.1111\/1574-6968.12107-BIB0031|fml12107-cit-0031","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1128\/JB.00109-08","article-title":"Genomic and functional analysis of ICEPdaSpa1, a fish-pathogen-derived SXT-related integrating conjugative element that can mobilize a virulence plasmid","volume":"190","author":"Osorio","year":"2008","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0033|fml12107-cit-0033","first-page":"1839","article-title":"The effect of plasmid R391 and other IncJ plasmids on the survival of Escherichia coli after UV irradiation","volume":"130","author":"Pembroke","year":"1984","journal-title":"J Gen Microbiol"},{"key":"10.1111\/1574-6968.12107-BIB0034|fml12107-cit-0034","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1007\/s000180200002","article-title":"Association of different mobile elements to generate novel integrative elements","volume":"59","author":"Rice","year":"2002","journal-title":"Cell Mol Life Sci"},{"key":"10.1111\/1574-6968.12107-BIB0035|fml12107-cit-0035","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.1574-6976.2011.00294.x","article-title":"Combinatorial events of insertion sequences and ICE in Gram-negative bacteria","volume":"35","author":"Toleman","year":"2011","journal-title":"FEMS Microbiol Rev"},{"key":"10.1111\/1574-6968.12107-BIB0036|fml12107-cit-0036","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.1128\/jb.178.14.4157-4165.1996","article-title":"A new type of conjugative transposon encodes resistance to sulfamethoxazole, trimethoprim, and streptomycin in Vibrio cholerae O139","volume":"178","author":"Waldor","year":"1996","journal-title":"J Bacteriol"},{"key":"10.1111\/1574-6968.12107-BIB0037|fml12107-cit-0037","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1038\/nrmicro2382","article-title":"Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow","volume":"8","author":"Wozniak","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"10.1111\/1574-6968.12107-BIB0038|fml12107-cit-0038","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1371\/journal.pgen.1000786","article-title":"Comparative ICE Genomics: insights into the Evolution of the SXT\/R391 Family of ICEs","volume":"5","author":"Wozniak","year":"2009","journal-title":"PLoS Genet"}],"container-title":["FEMS Microbiology Letters"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/femsle\/article-pdf\/342\/1\/45\/19434656\/342-1-45.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,22]],"date-time":"2020-07-22T12:47:19Z","timestamp":1595422039000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/femsle\/article-lookup\/doi\/10.1111\/1574-6968.12107"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,7]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,5]]}},"URL":"https:\/\/doi.org\/10.1111\/1574-6968.12107","relation":{},"ISSN":["0378-1097"],"issn-type":[{"value":"0378-1097","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3,7]]}}}