{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T13:17:26Z","timestamp":1772803046886,"version":"3.50.1"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,5,4]],"date-time":"2015-05-04T00:00:00Z","timestamp":1430697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001078","name":"Queensland Emergency Medicine Research Foundation","doi-asserted-by":"publisher","award":["na"],"award-info":[{"award-number":["na"]}],"id":[{"id":"10.13039\/501100001078","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Shortness of breath is a common reason for <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> attendance. This international study aims to describe the epidemiology of dyspnoea presenting to <jats:styled-content style=\"fixed-case\">EDs<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>outh <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>ast <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>sia\u2010<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>acific region, to compare disease patterns across regions, to understand how conditions are investigated and treated, and to assess quality of care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods\/Design<\/jats:title><jats:p>This is a prospective, interrupted time series cohort study conducted in <jats:styled-content style=\"fixed-case\">EDs<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia, <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand, <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>ingapore, <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>ong <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>ong and <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>alaysia of consecutive adult patients presenting to the <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> with dyspnoea as a main symptom. Data were collected over three 72 h periods in <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ay, <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ugust and <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>ctober 2014 (autumn, winter and spring), and included demographics, comorbidities, mode of arrival, usual medications, pre\u2010hospital treatment, initial assessment, <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> investigations, treatment in the <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>, <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> diagnosis, disposition from <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>, in\u2010hospital outcome and final hospital diagnosis. The primary outcomes of interest are the epidemiology and outcome of patients presenting to <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content> with dyspnoea. Secondary outcomes of interest are seasonal and geographic comparisons of diagnoses and outcomes, disease\u2010specific descriptions of epidemiology, investigation, treatment and disposition, and compliance with treatment guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>This novel study will explore dyspnoea from the viewpoint of the patient's symptom (shortness of breath) rather than that of a single disease. The results will provide robust data about the epidemiology, investigation, treatment and disposition of this diverse patient group. The obtained data also have the potential to inform service planning and to quantify the proportion of patients with mixed cardiac and respiratory disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.12397","type":"journal-article","created":{"date-parts":[[2015,5,4]],"date-time":"2015-05-04T10:47:44Z","timestamp":1430736464000},"page":"187-191","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Asia, Australia and <scp>N<\/scp>ew <scp>Z<\/scp>ealand Dyspnoea in Emergency Departments (<scp>AANZDEM<\/scp>) study: Rationale, design and analysis"],"prefix":"10.1111","volume":"27","author":[{"given":"Anne\u2010Maree","family":"Kelly","sequence":"first","affiliation":[{"name":"Joseph Epstein Centre for Emergency Medicine Research @ Western Health Sunshine Hospital  Melbourne Victoria Australia"},{"name":"Faculty of Medicine Dentistry and Health Sciences The University of Melbourne  Melbourne Victoria 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SAR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Craig","sequence":"additional","affiliation":[{"name":"Emergency Department Monash Medical Centre  Melbourne Victoria Australia"},{"name":"School of Clinical Sciences Monash University  Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Win Sen","family":"Kuan","sequence":"additional","affiliation":[{"name":"Emergency Medicine Department National University Health System  Singapore"},{"name":"Department of Surgery Yong Loo Lin School of Medicine National University of Singapore  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Auckland City Hospital  Auckland New 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