{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T12:47:44Z","timestamp":1777034864110,"version":"3.51.4"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T00:00:00Z","timestamp":1430179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>It is unclear whether emerging evidence for harm from aggressive fluid resuscitation for paediatric sepsis has altered clinical practice. We surveyed senior emergency physicians to see if their fluid resuscitation practices conformed to published clinical guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a cross\u2010sectional, Internet\u2010based survey of senior emergency medical staff in any of 12 <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>aediatric <jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>esearch in <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>mergency <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>epartments <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content>nternational <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ollaborative (<jats:styled-content style=\"fixed-case\">PREDICT<\/jats:styled-content>) <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>etwork centres in <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ustralia and <jats:styled-content style=\"fixed-case\">N<\/jats:styled-content>ew <jats:styled-content style=\"fixed-case\">Z<\/jats:styled-content>ealand.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 110 of 120 (92%) senior medical staff who responded. Ninety\u2010eight per cent of respondents used 0.9% saline as their primary resuscitation fluid. Sixty\u2010two per cent of respondents used 20 mL\/kg fluid bolus for every bolus, 30% used 20 mL\/kg for the first bolus and 10 mL\/kg subsequently. Response to fluid bolus administration was based on clinical parameters in 92% of respondents (heart rate, BP, skin perfusion\/mottling and central capillary refill), conscious state in 80% and venous lactate in 75%. Harm from fluid bolus administration was routinely monitored for by 81% of respondents. In those assessing for harm, clinical parameters were reported to be most commonly used (respiratory rate and effort in 60%, <jats:styled-content style=\"fixed-case\">SpO<jats:sub>2<\/jats:sub><\/jats:styled-content> in 55%, presence of crackles on lung auscultation in 50% and hepatomegaly in 42%). Invasive or ultrasound\u2010based monitoring was used infrequently.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Paediatric sepsis is reported to be managed by senior emergency physicians largely according to published guidelines. At this time, evidence for potential harm from fluid bolus resuscitation has not altered practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.12400","type":"journal-article","created":{"date-parts":[[2015,4,28]],"date-time":"2015-04-28T10:10:09Z","timestamp":1430215809000},"page":"245-250","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Fluid resuscitation for paediatric sepsis: A survey of senior emergency physicians in Australia and New Zealand"],"prefix":"10.1111","volume":"27","author":[{"given":"Elliot","family":"Long","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine The Royal Children's Hospital  Melbourne Victoria Australia"},{"name":"Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Department of Paediatrics Faculty of Medicine, Dentistry, and Health Sciences The University of Melbourne  Melbourne Victoria 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