{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:01:21Z","timestamp":1762999281526,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T00:00:00Z","timestamp":1496188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001349","name":"National Medical Research Council, Singapore","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001349","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001350","name":"Ministry of Health, Singapore","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001350","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control and Prevention","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>We aimed to investigate the effect of known heart disease on post\u2010out\u2010of\u2010hospital cardiac arrest (<jats:styled-content style=\"fixed-case\">OHCA<\/jats:styled-content>) survival outcomes, and its association with factors influencing survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was an observational, retrospective study involving an <jats:styled-content style=\"fixed-case\">OHCA<\/jats:styled-content> database from seven Asian countries in 2009\u20132012. Heart disease was defined as a documented diagnosis of coronary artery disease or congenital heart disease. Patients with non\u2010traumatic arrests for whom resuscitation was attempted and with known medical histories were included. Differences in demographics, arrest characteristics and survival between patients with and without known heart disease were analysed. Multivariate logistic regression was performed to identify factors influencing survival to discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 19 044 eligible patients, 5687 had known heart disease. They were older (77 <jats:italic>vs<\/jats:italic> 72 years) and had more comorbidities like diabetes (40.9 <jats:italic>vs<\/jats:italic> 21.8%), hypertension (60.6 <jats:italic>vs<\/jats:italic> 36.0%) and previous stroke (15.2 <jats:italic>vs<\/jats:italic> 10.1%). However, they were not more likely to receive bystander cardiopulmonary resuscitation (<jats:italic>P<\/jats:italic> = 0.205) or automated external defibrillation (<jats:italic>P<\/jats:italic> = 0.980). On univariate analysis, known heart disease was associated with increased survival (unadjusted odds ratio 1.16, 95% confidence interval 1.03\u20131.30). However, on multivariate analysis, heart disease predicted poorer survival (adjusted odds ratio 0.76, 95% confidence interval 0.58\u20131.00). Other factors influencing survival corresponded with previous reports.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Known heart disease independently predicted poorer post\u2010<jats:styled-content style=\"fixed-case\">OHCA<\/jats:styled-content> survival. This study may provide information to guide future prospective studies specifically looking at family education for patients with heart disease and the effect on <jats:styled-content style=\"fixed-case\">OHCA<\/jats:styled-content> outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.12809","type":"journal-article","created":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:19:08Z","timestamp":1496276348000},"page":"67-76","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Effect of known history of heart disease on survival outcomes after out\u2010of\u2010hospital cardiac arrests"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3371-6673","authenticated-orcid":false,"given":"Magdalene HM","family":"Lee","sequence":"first","affiliation":[{"name":"MOH Holdings Pte Ltd  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Fook\u2010Chong","sequence":"additional","affiliation":[{"name":"Division of Research Singapore General Hospital  Singapore"},{"name":"Centre for Quantitative Medicine Duke\u2010NUS Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Win","family":"Wah","sequence":"additional","affiliation":[{"name":"Saw Swee Hock School of Public Health National University of Singapore  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Do","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Seoul National University Hospital  Seoul Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Nishiuchi","sequence":"additional","affiliation":[{"name":"Department of Acute Medicine Kinki University Faculty of Medicine  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick Chow\u2010In","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine National Taiwan University Hospital  Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam Yasin","family":"Naroo","sequence":"additional","affiliation":[{"name":"Department of Health and Medical Services Rashid Hospital  Dubai United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwanhathai Darin","family":"Wong","sequence":"additional","affiliation":[{"name":"Emergency Department Hospital Pulau Pinang  Pulau Pinang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Tiah","sequence":"additional","affiliation":[{"name":"Accident and Emergency Department Changi General Hospital  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Apichaya","family":"Monsomboon","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Siriraj Hospital  Bangkok Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fahad J","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Singapore Clinical Research Institute  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus EH","family":"Ong","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Singapore General Hospital  Singapore"},{"name":"Health Services and Systems Research Duke\u2010NUS Medical School  Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the PAROS Clinical Research Network","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.08.006"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2005.10.002"},{"key":"e_1_2_8_4_1","first-page":"1286","article-title":"Cardiac arrest and cardiopulmonary resuscitation outcome reports: update of the Utstein Resuscitation Registry templates for out\u2010of\u2010hospital cardiac arrest: a statement for healthcare professionals from a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia); 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