{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T22:59:08Z","timestamp":1787785148121,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100014470","name":"Mundipharma International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014470","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Although most unintentional opioid deaths in Australia are attributed to pharmaceutical opioids, take\u2010home naloxone (THN) programmes have to date predominantly targeted people using illicit opioids in drug treatment and harm reduction settings. We sought to examine the feasibility of delivering THN brief interventions (THN\u2010BIs) with intranasal naloxone in EDs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This pilot feasibility study was conducted across three major metropolitan EDs in Sydney and Melbourne. ED staff were surveyed about their perspectives regarding THN before completing a 30\u2010min training programme in THN\u2010BI delivery. Patients presenting with opioid overdose or considered high risk for future overdose were eligible to receive the THN\u2010BI. Staff survey responses were compared between hospitals and provider types using one\u2010way analysis of variances. Patient demographic and clinical characteristics were extracted from medical records and compared between hospitals and overdose type using Fisher's exact test and one\u2010way analysis of variances.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred and twenty\u2010two ED staff completed the survey. One hundred and ten (90.2%) agreed that EDs should provide THN\u2010BIs, whereas 23 (19.2%) identified time constraints and 17 (12.9%) felt uncomfortable discussing overdose with patients. Fifty\u2010seven patients received the THN\u2010BI, with the majority (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200950, 87.7%) having presented following opioid overdose. The median age was 44\u2009years and 40 (71.4%) were men. Two\u2010thirds of the overdoses (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200931, 66.0%) were attributed to heroin with one\u2010third (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u200916, 34%) being attributed to pharmaceutical opioids.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ED\u2010based delivery of THN\u2010BIs can reach a wide range of individuals at\u2010risk of overdose. The present study supports the feasibility of THN interventions in EDs and underscores the importance of addressing implementation barriers including staff training.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1742-6723.13925","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T19:34:11Z","timestamp":1642016051000},"page":"509-518","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Overdose and take\u2010home naloxone in emergency settings: A pilot study examining feasibility of delivering brief interventions addressing overdose prevention with \u2018take\u2010home naloxone\u2019 in emergency departments"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6291-8568","authenticated-orcid":false,"given":"Eleanor","family":"Black","sequence":"first","affiliation":[{"name":"Drug and Alcohol Services, South Eastern Sydney Local Health 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