{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:08:23Z","timestamp":1791274103823,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:00:00Z","timestamp":1645574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the local experience of adult patients presenting with cannabinoid hyperemesis syndrome (CHS) to an urban ED in the outer northern suburbs of Melbourne.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective chart review of adult patients presenting to the ED with a documented history of CHS or equivalent terminology from January 2015 to January 2021. Age, sex, cannabis use, clinical features, pathology results, imaging and symptomatic management were examined as well as outcomes regarding disposition, representation, morbidity and mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and forty\u2010two adult presentations were included. Sixty\u2010seven were unique presentations and 29 were patients who represented during the study period. Most represented within 3\u00a0months (37.8%) and most represented at least twice. Males were overrepresented (68.7%). Patients were young (median age 31 years, interquartile range 23\u201335 years) and all had a history of regular cannabis use (usually daily). Cyclical nausea and\/or vomiting was the most common clinical feature compared to others in previously reported diagnostic criteria. Patients typically had elevated white cell counts with associated neutrophilia (75.8%) and mild hypokalaemia (57.9%). Lipase was not elevated, and C\u2010reactive protein was typically less than 50\u2009mmol\/L (98.2%). Imaging was not commonly performed but largely normal. Treatment was supportive with anti\u2010emetic use, intravenous fluids and analgesia. There were no deaths or admissions to intensive care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cyclical nausea and vomiting was the most common feature observed in this cohort compared to other clinical features reported in prior studies. Serum lipase was normal and C\u2010reactive protein only mildly elevated. Prospective studies are required to further assess these findings.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.13944","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T01:33:06Z","timestamp":1645666386000},"page":"578-583","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cannabinoid hyperemesis syndrome: A 6\u2010year audit of adult presentations to an urban district hospital"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2068-8757","authenticated-orcid":false,"given":"Joe A","family":"Rotella","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivia G","family":"Ferretti","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham","family":"Raisi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao Rui","family":"Seet","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soham","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Northern Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13181-016-0595-z"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/can.2019.0059"},{"key":"e_1_2_9_4_1","first-page":"574","article-title":"Improving the diagnosis of cannabinoid hyperemesis syndrome","volume":"111","author":"Burillo PGD\u2010A","year":"2019","journal-title":"Rev. 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