{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T10:25:57Z","timestamp":1790850357515,"version":"4.1.0"},"reference-count":5,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,4,9]],"date-time":"2022-04-09T00:00:00Z","timestamp":1649462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To determine the relationship between arterial and venous acid\u2013base status in a model of septic shock.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Paired samples (<jats:italic>n<\/jats:italic>\u00a0=\u2009435) of arterial and femoral venous blood from 57 sheep (47 septic, 10 non\u2010septic) managed with protocol\u2010guided ventilation, sedation, parenteral fluids and inotropic support.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The arterial\u2010venous difference in acid\u2013base parameters was similar with and without sepsis. There was a consistent arterio\u2010venous relationship for metabolic (pH, lactate, bicarbonate, base excess), but not respiratory parameters (partial pressures of oxygen, carbon dioxide, and haemoglobin\u2010oxygen saturation), independent of sepsis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Venous blood provides a reliable measure of metabolic but not respiratory disturbance.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.13975","type":"journal-article","created":{"date-parts":[[2022,4,10]],"date-time":"2022-04-10T00:59:00Z","timestamp":1649552340000},"page":"456-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Venous blood for the analysis of acid\u2013base status in a model of septic shock"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4345-3213","authenticated-orcid":false,"given":"Matthew J","family":"Maiden","sequence":"first","affiliation":[{"name":"Intensive Care Unit, Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Acute Care Medicine The University of Adelaide  Adelaide South Australia Australia"},{"name":"Intensive Care Unit Barwon Health  Geelong Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D","family":"Fraser","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Acute Care Medicine The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E","family":"Finnis","sequence":"additional","affiliation":[{"name":"Intensive Care Unit, Royal Adelaide Hospital  Adelaide South Australia Australia"},{"name":"Discipline of Acute Care Medicine The University of Adelaide  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,9]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-6723.2010.01344.x"},{"key":"e_1_2_8_3_1","first-page":"253","article-title":"Arteriovenous blood gas agrement in intensive care patents with varying levels of circulatory compromise: a pilot study","volume":"17","author":"Hynes D","year":"2015","journal-title":"Crit. Care Resusc."},{"key":"e_1_2_8_4_1","first-page":"269","article-title":"Utility of venous blood gases in severe sepsis and septic shock","volume":"31","author":"White HD","year":"2018","journal-title":"Proc. (Bayl. Univ. Med. Cent.)"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000001644"},{"key":"e_1_2_8_6_1","unstructured":"Clinical and Laboratory Standards Institute.Blood Gas and pH Analysis and Related Measurements; Approved Guideline; CLSI Document C46\u2010A2; (Vol. 29 No. 8); Feb 2009."}],"container-title":["Emergency Medicine Australasia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1742-6723.13975","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1742-6723.13975","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1742-6723.13975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:59:16Z","timestamp":1692849556000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1742-6723.13975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,9]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/1742-6723.13975"],"URL":"https:\/\/doi.org\/10.1111\/1742-6723.13975","archive":["Portico"],"relation":{},"ISSN":["1742-6731","1742-6723"],"issn-type":[{"value":"1742-6731","type":"print"},{"value":"1742-6723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,9]]},"assertion":[{"value":"2021-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}