{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:47:25Z","timestamp":1756464445816,"version":"3.40.5"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T00:00:00Z","timestamp":1650844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100002076","name":"Emergency Medicine Foundation","doi-asserted-by":"publisher","award":["EMSS\u2010227R24\u20102015"],"award-info":[{"award-number":["EMSS\u2010227R24\u20102015"]}],"id":[{"id":"10.13039\/100002076","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Paediatric status epilepticus (SE) has potential for long\u2010term sequelae. Existing data demonstrate delays to aspects of care. The objective of the present study was to examine the feasibility of collecting data on children with paediatric SE and describe current management strategies in pre\u2010hospital and in\u2010hospital settings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A pilot, prospective, observational cohort study of children 4\u2009weeks to 16\u2009years of age with SE, in four EDs in Australia. Clinical details including medications administered, duration of seizure and short\u2010term outcomes were collected. Follow up occurred by telephone at 1 month.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 167 children with SE. Mean age was 5.4\u2009years (standard deviation [SD]\u00a04.1), and 81 (49%) male. Median seizure duration was 10\u00a0min (interquartile range\u00a07\u201330). Midazolam was the first medication administered in 87\/100 (87%) instances, mean dose of 0.21\u2009mg\/kg (SD\u00a00.13). The dose of midazolam was adequate in 30 (35%), high (&gt;0.2\u00a0mg\/kg) in 44 (51%) and low (&lt;0.1\u00a0mg\/kg) in 13 (15%). For second\u2010line agents, levetiracetam was administered on 33\/55 (60%) occasions, whereas phenytoin and phenobarbitone were administered on 11\/55 (20%) occasions each. Mean dose of levetiracetam was 26.4\u00a0mg\/kg (SD\u00a013.5). One hundred and four (62%) patients were admitted to hospital, with 13 (8%) admitted to ICU and seven (4%) intubated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In children presenting with SE in Australia medical management differed from previous reports, with midazolam as the preferred benzodiazepine, and levetiracetam replacing phenytoin as the preferred second\u2010line agent. This pilot study indicates the feasibility of a paediatric SE registry and its utility to understand and optimise practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.13988","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T07:09:25Z","timestamp":1650870565000},"page":"801-807","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Status Epilepticus Australasian Registry for Children: A pilot prospective, observational, cohort study of paediatric status epilepticus"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9503-0928","authenticated-orcid":false,"given":"Jeremy S","family":"Furyk","sequence":"first","affiliation":[{"name":"Emergency Department The Townsville Hospital  Townsville Queensland Australia"},{"name":"Emergency Department University Hospital Geelong  Geelong Victoria Australia"},{"name":"School of Medicine Deakin University  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I","family":"Emeto","sequence":"additional","affiliation":[{"name":"College of Public Health, Medical and Veterinary Sciences James Cook University  Townsville Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerrianne","family":"Watt","sequence":"additional","affiliation":[{"name":"College of Public Health, Medical and Veterinary Sciences James Cook University  Townsville Queensland Australia"},{"name":"Queensland Ambulance Service  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharon","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Emergency Department Perth Children's Hospital  Perth Western Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate","family":"Riney","sequence":"additional","affiliation":[{"name":"Neurosciences Unit Children's Health Queensland\/School of Medicine, The University of Queensland  Brisbane Queensland 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Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart R","family":"Dalziel","sequence":"additional","affiliation":[{"name":"Emergency Department Starship Children's Hospital  Auckland New Zealand"},{"name":"Departments of Surgery and Paediatrics: Child and Youth Health The University of Auckland  Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1107-2187","authenticated-orcid":false,"given":"Franz E","family":"Babl","sequence":"additional","affiliation":[{"name":"Clinical Sciences Murdoch Children's Research Institute  Melbourne Victoria Australia"},{"name":"Departments of Paediatrics and Critical Care The University of Melbourne  Melbourne Victoria Australia"},{"name":"Emergency Department The Royal Children's Hospital Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on\u2009behalf\u2009of the Paediatric Research in Emergency 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