{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T17:29:14Z","timestamp":1792517354701,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T00:00:00Z","timestamp":1737590400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["MRF2007671"],"award-info":[{"award-number":["MRF2007671"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To establish the determinants of death in hospital for patients with moderate to severe traumatic brain injury (TBI) in Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, setting, participants<\/jats:title><jats:p>Retrospective analysis of Australia New Zealand Trauma Registry (ANZTR) data. Cases were included if they presented to a participating hospital between 1 July 2015 and 30 June 2020 and had an Abbreviated Injury Severity (AIS) score \u2013 head greater than 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>Death in hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 16\u2009350 patients. Their mean age was 51\u2009years and 71% were male. After adjusting for measures of injury severity, there was an increased odds of in\u2010hospital death for patients whose injury occurred outside daylight hours or first mode of transport was road ambulance, who were not transferred from another hospital, had an endotracheal tube placed prior to definitive hospital arrival or received their definitive hospital care outside Victoria.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Among people presenting to a major trauma hospital in Australia following moderate to severe TBI, there were multiple factors independently associated with death in hospital. The potentially modifiable determinants of in\u2010hospital death included out\u2010of\u2010hours access to emergency care, mode of transfer from the scene of the injury, prior facility care and pre\u2010definitive hospital endotracheal intubation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1742-6723.14562","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T08:33:36Z","timestamp":1737621216000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The determinants for death in hospital following moderate to severe traumatic brain injury in Australia"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5763-917X","authenticated-orcid":false,"given":"Gerard M","family":"O'Reilly","sequence":"first","affiliation":[{"name":"National Trauma Research Institute, Alfred Health  Melbourne Victoria Australia"},{"name":"Emergency and Trauma Centre, Alfred Health  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