{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:42:27Z","timestamp":1792762947160,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T00:00:00Z","timestamp":1762300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To validate and simplify Marois Severity Score (MSS) for improved usability in the emergency department (ED) setting, and to compare its predictive accuracy with a newly developed Dengue Simplified Severity Score (D\u2010SSS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, observational study included adult patients presenting with laboratory\u2010confirmed dengue to Universiti Malaya Medical Centre ED from January 2023 to December 2023. D\u2010SSS was developed by modifying MSS. The scoring system incorporated age, hypertension, mucosal bleeding, thrombocytopenia, and elevated ALT levels. D\u2010SSS and MSS were evaluated for accuracy in predicting severe dengue according to the World Health Organisation 2009 classification using receiver operating characteristic (ROC) analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 507 eligible patients, 350 were analysed. D\u2010SSS, with a cut\u2010off value of 2.5, demonstrated 80.0% (95% CI: 51.91, 95.67) sensitivity and 75.5% (95% CI: 70.55, 80.03) specificity in predicting severe dengue. Its discriminative ability (AUC: 0.856) was numerically higher but not statistically different from MSS (AUC: 0.782;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.335, DeLong's test).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>D\u2010SSS provides an accurate and more practical tool for predicting severe dengue in the ED. Its simplified design enhances applicability, facilitating earlier intervention and potentially improving patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1742-6723.70158","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T07:52:20Z","timestamp":1762415540000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Development and Validation of the Dengue Simplified Severity Score Based on the Marois Severity Score for Predicting Severe Dengue in the Emergency Department"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5458-6596","authenticated-orcid":false,"given":"Kaur Dhesi","family":"Preetvinder","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Faculty of Medicine, Universiti Malaya  Lembah Pantai Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1374-5012","authenticated-orcid":false,"given":"Khadijah","family":"Poh","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Faculty of Medicine, Universiti Malaya  Lembah Pantai Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9403-0734","authenticated-orcid":false,"given":"Aida","family":"Bustam","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Faculty of Medicine, Universiti Malaya  Lembah Pantai Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8431-8459","authenticated-orcid":false,"given":"Aliyah","family":"Zambri","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Faculty of Medicine, Universiti Malaya  Lembah Pantai Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1085-0725","authenticated-orcid":false,"given":"Muhaimin","family":"Noor Azhar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Faculty of Medicine, Universiti Malaya  Lembah Pantai Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taab146"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2022.09.006"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0012071"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1110265"},{"key":"e_1_2_11_6_1","volume-title":"Dengue Guidelines for Diagnosis, Treatment, Prevention and Control: New Edition","author":"World Health Organization","year":"2009"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40249-021-00908-2"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.5005\/japi-11001-0095"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.09.1321"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/845876"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002533"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879\u2010021\u201006146\u2010z"},{"key":"e_1_2_11_13_1","unstructured":"Health IfP \u201cNational Health and Morbidity Survey (NHMS) 2019: Vol. I: NCDs\u2013Non\u2010Communicable Diseases: Risk Factors and Other Health Problems \u201dMinistry of Health Malaysia Putrajaya Malaysia 2020."},{"key":"e_1_2_11_14_1","unstructured":"H.RitchieandM.Roser \u201cAlcohol Consumption \u201dOur World in Data 2023."},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/tropicalmed8080409"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2015.05.006"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2014.02.013"},{"key":"e_1_2_11_18_1","volume-title":"Statistics With Confidence","author":"Altman D. 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