{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T10:46:07Z","timestamp":1782816367228,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T00:00:00Z","timestamp":1781222400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Emerg Medicine Australasia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Hypocalcaemia is a common electrolyte disturbance in major trauma patients, particularly those with haemorrhagic shock. Trauma patients are often intubated as part of their care, which can result in post\u2010induction hypotension. We aimed to estimate the effect of hypocalcaemia on post\u2010induction hypotension.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective observational study of trauma patients \u2265\u200918\u2009years old intubated in a tertiary Australian Emergency Department between 1st January 2020 and 30th September 2024. Epidemiological and clinical management data were extracted to estimate the effect of hypocalcaemia on outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 478 eligible patients, 151 had available haemodynamic and calcium measurements. Post\u2010induction hypotension occurred in 38\/47 (81%) of hypocalcaemic and 69\/104 (66%) of non\u2010hypocalcaemic patients. Hypocalcaemia was associated with higher odds of post\u2010induction hypotension (adjusted odds ratio [aOR] 2.15, 95% confidence interval [CI] 0.84\u20135.51), with considerable uncertainty in this estimate. Hypocalcaemic patients were more likely to receive red blood cells within 15\u2010min post\u2010induction (OR 2.13, 95% CI 1.12\u20134.04). Minimal differences were observed in cardiac arrest 15\u2010min post\u2010induction (OR 0.65, 95% CI 0.07\u20135.73) or mortality at discharge (OR 1.00, 95% CI 0.51\u20131.97).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Hypocalcaemia may be associated with higher odds of post\u2010induction hypotension in trauma patients; however, our findings require corroboration across a larger multi\u2010centre prospective observational study. If corroborated, a randomised controlled trial is warranted to establish the utility of calcium replacement for the prevention of post\u2010induction hypotension.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1742-6723.70300","type":"journal-article","created":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T01:08:35Z","timestamp":1781312915000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Influence of Hypocalcaemia on Trauma Patients Experiencing Post\u2010Induction Hypotension: A Retrospective Observational Study"],"prefix":"10.1111","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-1003-0121","authenticated-orcid":false,"given":"Andy","family":"Kwok","sequence":"first","affiliation":[{"name":"Department of Critical Care University of Melbourne  Melbourne Australia"},{"name":"Department of Emergency Medicine Royal Melbourne Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1277-5538","authenticated-orcid":false,"given":"Chris","family":"Selman","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Biostatistics Unit Murdoch Children's Research Institute  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1152-5851","authenticated-orcid":false,"given":"Kellie","family":"Gumm","sequence":"additional","affiliation":[{"name":"Trauma Service Royal Melbourne Hospital  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Read","sequence":"additional","affiliation":[{"name":"Trauma Service Royal Melbourne Hospital  Melbourne Australia"},{"name":"Department of Surgery University of Melbourne  Melbourne 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