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The niche provides signaling molecules to control the survival, self\u2010renewal, and differentiation of stem cells. As tissues generally contain different types of stem cells, it is important to understand how these stem cells are coordinately regulated by various signaling pathways. The\n                    <jats:italic>Drosophila<\/jats:italic>\n                    testis niche serves as an excellent model for studying such processes, because it harbors 2 types of stem cells, germline stem cells and somatic cyst stem cells. In this review, we summarize the roles of key signaling pathways in stem cell maintenance and differentiation in the\n                    <jats:italic>Drosophila<\/jats:italic>\n                    testis.\n                  <\/jats:p>","DOI":"10.1111\/1744-7917.70072","type":"journal-article","created":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T02:08:42Z","timestamp":1747793322000},"page":"1285-1294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Signaling pathways in\n                    <i>Drosophila<\/i>\n                    testis niche: Local signals that regulate stem cell fate"],"prefix":"10.1111","volume":"33","author":[{"given":"Ting","family":"Zhao","sequence":"first","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology Guangzhou Key Laboratory of Insect Development Regulation and Application Research Institute of Insect Science and Technology School of Life Sciences South China Normal University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1419-9009","authenticated-orcid":false,"given":"Xiao\u2010Qiang","family":"Yu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Insect Developmental Biology and Applied Technology Guangzhou Key Laboratory of Insect Development Regulation and Application Research Institute of Insect Science and Technology School of Life Sciences South China Normal University  Guangzhou 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