{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T07:26:31Z","timestamp":1792135591405,"version":"4.4.0"},"reference-count":192,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010665","name":"H2020 Marie Sk\u0142odowska-Curie Actions","doi-asserted-by":"publisher","award":["859850"],"award-info":[{"award-number":["859850"]}],"id":[{"id":"10.13039\/100010665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Insect Science"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Iflaviruses are arthropod\u2010infecting viruses classified in the family\n                    <jats:italic>Iflaviridae<\/jats:italic>\n                    . The most well\u2010studied iflaviruses are responsible for deleterious overt (symptomatic) infections in economically important insect species like honeybees and silkworms. The fact that iflaviruses are also found in mass reared insects such as crickets and flies, makes their study relevant for the food and feed industries and for biological control applications (e.g., mass reared insects for sterile insect techniques). In recent years it was found that iflaviruses are not restricted to insects, but are widely spread in many arthropod species, often causing covert (asymptomatic) infections. Fitness costs may be associated with these covert infections, as seen in a variety of host species. In this work we review the latest research on iflaviruses in respect to host range, viral genome organization, cycle of infection, tissue tropism, virus transmission strategies, fitness costs and pathogenic effects of both covert and overt infections, host immune responses to iflavirus infections, interactions between iflaviruses and other microorganisms, and the effect of iflavirus infections on host behavior.\n                  <\/jats:p>","DOI":"10.1111\/1744-7917.70177","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T06:40:14Z","timestamp":1760510414000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Iflaviruses in arthropods: when small is mighty"],"prefix":"10.1111","author":[{"given":"Annamaria","family":"Mattia","sequence":"first","affiliation":[{"name":"Laboratory of Virology Wageningen University &amp; Research  Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah\u2010Isadora","family":"Huditz","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Wageningen University &amp; Research  Wageningen The Netherlands"},{"name":"Insect Pest Control Laboratory, Joint FAO\/IAEA Programme of Nuclear Techniques in Food and Agriculture International Atomic Energy Agency, Vienna International Centre  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6664-4445","authenticated-orcid":false,"given":"Monique M.","family":"van Oers","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Wageningen University &amp; Research  Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4831-7299","authenticated-orcid":false,"given":"Vera I.D.","family":"Ros","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Wageningen University &amp; Research  Wageningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/s12917-019-1823-y","article-title":"Immune related genes as markers for monitoring health status of honey bee colonies","volume":"15","author":"Barroso\u2010Ar\u00e9valo S.","year":"2019","journal-title":"BMC Veterinary Research"},{"key":"e_1_2_15_3_1","doi-asserted-by":"crossref","DOI":"10.1098\/rspb.2016.2149","article-title":"Covert deformed wing virus infections have long\u2010term deleterious effects on honeybee foraging and survival","volume":"284","author":"Benaets K.","year":"2017","journal-title":"Proceedings of the Royal Society B: Biological Sciences"},{"key":"e_1_2_15_4_1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1461-0248.2005.00722.x","article-title":"Parasites hinder 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