{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T08:29:05Z","timestamp":1763972945156,"version":"3.45.0"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T00:00:00Z","timestamp":1763942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270522","32500410","32400390"],"award-info":[{"award-number":["32270522","32500410","32400390"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Insect Science"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Pests are a major cause of agricultural and economic losses. Their high reproduction rate remains a considerable challenge for pest control. Insects with impaired border cell migration during oogenesis are unable to reproduce, offering a potential method to reduce their population growth. To fully understand the effects of the deubiquitinating enzyme (DUB) family on border cell migration, we generated 38 transgenic fly lines overexpressing distinct DUBs, using Gal4\/UAS technology to drive their expression in border cells. Overexpression of\n                    <jats:italic>usp10<\/jats:italic>\n                    led to reductions in ovary size, egg production, and egg hatchability. Interestingly, knockdown of\n                    <jats:italic>usp10<\/jats:italic>\n                    also resulted in the same defects, indicating the importance of maintaining proper Usp10 levels for oogenesis. In addition, the immunofluorescence and confocal microscopy analysis revealed that either overexpression or knockdown of\n                    <jats:italic>usp10<\/jats:italic>\n                    disrupts adherens junctions and actin filament distribution, ultimately leading to delayed border cell migration. Taken together, this study highlights the critical role of Usp10 in\n                    <jats:italic>Drosophila<\/jats:italic>\n                    fertility, and suggests Usp10 as a potential target for pest management.\n                  <\/jats:p>","DOI":"10.1111\/1744-7917.70197","type":"journal-article","created":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T08:24:56Z","timestamp":1763972696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The deubiquitinase Usp10 regulates\n                    <i>Drosophila<\/i>\n                    reproduction through modulating border cell migration"],"prefix":"10.1111","author":[{"given":"Fengyun","family":"Lei","sequence":"first","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation and Bioresource Utilization of Jiangxi Province College of Life Sciences Jiangxi Normal University  Nanchang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohan","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Life Sciences and Medicine Shandong University of Technology  Zibo Shandong Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation and Bioresource Utilization of Jiangxi Province College of Life Sciences Jiangxi Normal University  Nanchang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation and Bioresource Utilization of Jiangxi Province College of Life Sciences Jiangxi Normal University  Nanchang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5883-8218","authenticated-orcid":false,"given":"Zizhang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation and Bioresource Utilization of Jiangxi Province College of Life Sciences Jiangxi Normal University  Nanchang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinkai","family":"Tong","sequence":"additional","affiliation":[{"name":"Key Laboratory of Biodiversity Conservation and Bioresource Utilization of Jiangxi Province College of Life Sciences Jiangxi Normal University  Nanchang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202007005","article-title":"Drosophila USP22\/nonstop polarizes the actin cytoskeleton during collective border cell 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