{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:20:27Z","timestamp":1787905227534,"version":"build-2784847793"},"reference-count":59,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32371055"],"award-info":[{"award-number":["32371055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Insect Science"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Animals must continuously adapt their behavior to dynamic sensory environments and internal motor states. In\n                    <jats:italic>Drosophila<\/jats:italic>\n                    and other invertebrates, the mushroom body is key to this behavioral flexibility, with dopaminergic neurons (DANs) and mushroom body output neurons (MBONs) forming a core circuit for context\u2010dependent action selection. Yet, how olfactory cues and locomotor states are jointly integrated and transformed across the DAN\u2010MBON circuit is unclear. Using single\u2010 and dual\u2010color two\u2010photon calcium and dopamine imaging, we found distinct representations in the \u03b31 compartment. In response to prolonged food odor delivery, \u03b31 DANs exhibit transient responses tightly locked to odor onset and offset, whereas MBONs maintain a sustained response throughout odor delivery. Moreover, while spontaneous locomotion elicits faithful DAN calcium dynamics and dopamine release without clearly affecting MBONs, odor\u2010evoked locomotion selectively amplifies the transient and sustained olfactory responses in DANs and MBONs, respectively, facilitating context\u2010dependent olfactory\u2010motor integration. Linear encoding models reveal that DANs broadly integrate diverse olfactory and locomotor variables, and exhibit higher variability than MBONs. We propose a model where dopaminergic transients serve as context\u2010switch signals, integrating environmental and locomotor contexts to flexibly modulate sustained MBON output and guide behavior.\n                  <\/jats:p>","DOI":"10.1111\/1744-7917.70351","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T08:13:41Z","timestamp":1787904821000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sensory\u2010evoked locomotion selectively enhances transient and sustained food odor representations in a mushroom body dopaminergic circuit in\n                    <i>Drosophila<\/i>"],"prefix":"10.1111","author":[{"given":"Qiantao","family":"Lv","sequence":"first","affiliation":[{"name":"Zhejiang University Hangzhou China"},{"name":"Key Laboratory of Growth Regulation and Translational Research of Zhejiang Province and Research Center for Industries of the Future, School of Life 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