{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:16:10Z","timestamp":1768007770374,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,8,11]],"date-time":"2013-08-11T00:00:00Z","timestamp":1376179200000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2013,8]]},"abstract":"Abstract<\/jats:title>Chronic kidney disease (CKD<\/jats:styled-content>) is common and several factors affect its progression to end\u2010stage renal disease (ESRD<\/jats:styled-content>). The main goal of our study was to assess the influence of underlying kidney disease and some other important factors during the time of CKD<\/jats:styled-content> progression to ESRD<\/jats:styled-content>. A retrospective study of 91 patients (57 men, 34 women; average age 57.7\u2009\u00b1\u200913.2 years) was carried out. Patients were monitored at least one month before the first renal replacement treatment (RRT<\/jats:styled-content>). Estimated glomerular filtration rate (eGFR<\/jats:styled-content>) at first referral to nephrologist was determined by M<\/jats:styled-content>odification of D<\/jats:styled-content>iet in R<\/jats:styled-content>enal D<\/jats:styled-content>isease equation. Proteinuria was assessed semiquantitatively with dipsticks. Thirty\u2010five patients (38.5%) had diabetic nephropathy (DN<\/jats:styled-content>), 21 (23.1%) hypertensive nephrosclerosis (HN<\/jats:styled-content>), 21 (23.1%) adult polycystic kidney disease (APKD<\/jats:styled-content>) and 14 (15.4%) immunoglobulin A<\/jats:styled-content> nephropathy (IgAN<\/jats:styled-content>). Average eGFR<\/jats:styled-content> at first referral for DN<\/jats:styled-content> patients was 20.1, and then 23.4 for HN<\/jats:styled-content>, 35.5 for APKD<\/jats:styled-content>, and 36.4\u2009mL<\/jats:styled-content>\/min per 1,73\u2009m2<\/jats:sup> for IgAN<\/jats:styled-content> patients. Average time between first nephrological visit and first RRT<\/jats:styled-content> was 28.4 months for DN<\/jats:styled-content> patients, 41 for HN<\/jats:styled-content>, 80.8 for APKD<\/jats:styled-content>, and 70.1 for IgAN<\/jats:styled-content> patients. Comparison of all four groups of CKD<\/jats:styled-content> patients showed that in patients with APKD<\/jats:styled-content> and IgAN<\/jats:styled-content> impairment of kidney function to ESRD<\/jats:styled-content> had progressed statistically significantly slower (P<\/jats:italic>\u2009<\u20090.001). When eGFR<\/jats:styled-content> at referral, proteinuria, smoking, and renin\u2010angiontensin\u2010aldosterone blockade treatment had been added into the model, patients with APKD<\/jats:styled-content> and IgAN<\/jats:styled-content> had a statistically significant longer period between first nephrological visit and first RRT<\/jats:styled-content> (P<\/jats:italic>\u2009<\u20090.026). In comparison with patients with other underlying causes of CKD<\/jats:styled-content>, patients with APKD<\/jats:styled-content> and IgAN<\/jats:styled-content> had a statistically significant slower progression rate of CKD<\/jats:styled-content> to ESRD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1744-9987.12079","type":"journal-article","created":{"date-parts":[[2013,8,12]],"date-time":"2013-08-12T04:28:56Z","timestamp":1376281736000},"page":"363-367","source":"Crossref","is-referenced-by-count":16,"title":["Chronic Kidney Disease Progression to End Stage Renal Disease: A Single Center Experience of the Role of the Underlying Kidney Disease"],"prefix":"10.1111","volume":"17","author":[{"given":"Robert","family":"Ekart","sequence":"first","affiliation":[{"name":"Department of Dialysis Clinic for Internal Medicine University Medical Centre Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Ferjuc","sequence":"additional","affiliation":[{"name":"Medical Faculty University of Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Furman","sequence":"additional","affiliation":[{"name":"Medical Faculty University of Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0160pela","family":"Gerjevi\u010d","sequence":"additional","affiliation":[{"name":"Medical Faculty University of Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastjan","family":"Bevc","sequence":"additional","affiliation":[{"name":"Department of Nephrology Clinic for Internal Medicine University Medical Centre Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radovan","family":"Hojs","sequence":"additional","affiliation":[{"name":"Department of Nephrology Clinic for Internal Medicine University Medical Centre Maribor Maribor Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,8,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/kisup.2012.73"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.468"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041031"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001794"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.260"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.07.040"},{"key":"e_1_2_6_8_1","first-page":"1761","volume-title":"Harrison's Principles of Internal Medicine","author":"Kasper DL","year":"2008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-135-2-200107170-00007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006257"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2004.01122.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta14210"},{"key":"e_1_2_6_13_1","first-page":"9","article-title":"Relationship between nephrologist care and progression of chronic kidney disease","volume":"68","author":"Orlando LA","year":"2007","journal-title":"N C Med J"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00805-9"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.09.015"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.12.2357"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-137-6-200209170-00007"},{"issue":"2","key":"e_1_2_6_18_1","first-page":"S7","article-title":"K\/DOQI clinical practice guidelines for chronic kidney disease. Evaluation classification and stratification kidney disease outcomes quality initiative","volume":"39","author":"National Kidney Foundation","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2007.08.004"},{"key":"e_1_2_6_20_1","first-page":"831","volume-title":"Comprehensive Clinical Nephrology","author":"Feehally J","year":"2007"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1744-9987.12079","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.12079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T03:36:53Z","timestamp":1694489813000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.12079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/1744-9987.12079"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.12079","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}