{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:09:59Z","timestamp":1787170199062,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T00:00:00Z","timestamp":1397088000000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>\n \n The high prevalence of significant asymptomatic coronary artery disease (\n CAD<\/jats:styled-content>\n ) has been reported in patients with end\u2010stage renal disease (\n ESRD<\/jats:styled-content>\n ) at the initiation of dialysis. However, the approach to evaluate asymptomatic\n CAD<\/jats:styled-content>\n for these patients has not been established. The aim of this study is to assess the applicability of our practical approach at the initiation of dialysis. We prospectively enrolled 182 consecutive\n ESRD<\/jats:styled-content>\n patients who initiated dialysis. After echocardiography as primary screening, pharmacologic stress thallium\u2010201 scintigraphy and\/or coronary angiography (\n CAG<\/jats:styled-content>\n ) were performed to diagnose\n CAD<\/jats:styled-content>\n . The patients were classified into two groups: those with coronary artery stenosis by\n CAG<\/jats:styled-content>\n (\n CAD<\/jats:styled-content>\n + group), those without coronary artery stenosis by\n CAG<\/jats:styled-content>\n or with negative scintigraphy examination (\n CAD<\/jats:styled-content>\n \u2212 group). Of the eligible 93 patients without the history of\n CAD<\/jats:styled-content>\n , 22 patients were allocated to the\n CAD<\/jats:styled-content>\n + group (18 of 26 patients with abnormal echocardiography and 4 of 13 patients with positive scintigraphy examination) and 71 patients to the\n CAD<\/jats:styled-content>\n \u2212 group. Patients were followed up for an average of 520\u2009\u00b1\u2009304 days. The event\u2010free survival rate of major adverse cardiac events was significantly lower in the\n CAD<\/jats:styled-content>\n + group than in the\n CAD<\/jats:styled-content>\n \u2212 group (\n P<\/jats:italic>\n \u2009<\u20090.001). There was no cardiovascular event including major adverse cardiac events, unstable angina, coronary revascularization or stroke in the\n CAD<\/jats:styled-content>\n \u2212 group during the first year of dialysis. Patients without\n CAD<\/jats:styled-content>\n diagnosed by our approach had favorable clinical outcomes. Our approach may be useful for screening of occult\n CAD<\/jats:styled-content>\n in\n ESRD<\/jats:styled-content>\n patients at the initiation of dialysis.\n <\/jats:p>","DOI":"10.1111\/1744-9987.12098","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T22:51:04Z","timestamp":1397170264000},"page":"167-173","source":"Crossref","is-referenced-by-count":2,"title":["Practical Approach to Evaluate Asymptomatic Coronary Artery Disease in End\u2010Stage Renal Disease Patients at the Initiation of Dialysis"],"prefix":"10.1111","volume":"18","author":[{"given":"Akihito","family":"Tanaka","sequence":"first","affiliation":[{"name":"Department of Cardiology Nagoya University Graduate School of Medicine Nagoya Japan"},{"name":"Department of Cardiology Handa City Hospital Handa Japan"},{"name":"Department of Cardiology Okazaki City Hospital Okazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Sakakibara","sequence":"additional","affiliation":[{"name":"Department of Cardiology Handa City Hospital Handa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Asada","sequence":"additional","affiliation":[{"name":"Department of Nephrology Okazaki City Hospital Okazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshikazu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Cardiology Okazaki City Hospital Okazaki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Cardiology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toyoaki","family":"Murohara","sequence":"additional","affiliation":[{"name":"Department of Cardiology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,10]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"S16","article-title":"Epidemiology of cardiovascular disease in chronic renal disease","volume":"9","author":"Foley RN","year":"1998","journal-title":"J Am Soc 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