{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T17:24:56Z","timestamp":1775323496617,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T00:00:00Z","timestamp":1421884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2015,6]]},"abstract":"Abstract<\/jats:title>We evaluated the influence of kidney volume (KV<\/jats:styled-content>) and liver volume (LV<\/jats:styled-content>) on continuation of peritoneal dialysis (PD<\/jats:styled-content>) in patients with autosomal dominant polycystic kidney disease (PKD<\/jats:styled-content>). Twenty\u2010two PKD<\/jats:styled-content> patients on PD<\/jats:styled-content> were retrospectively investigated after being divided into two groups. Group 1 comprised 15 patients who started PD<\/jats:styled-content> at our hospital and group 2 was composed of seven patients referred from other hospitals for treatment of renomegaly by transcatheter arterial embolization (TAE<\/jats:styled-content>) at 47.1\u2009\u00b1\u200921.8 months after commencing PD<\/jats:styled-content>. In group 1, KV<\/jats:styled-content> for both kidneys (mean\u2009\u00b1\u2009SD<\/jats:styled-content>) was 2787\u2009\u00b1\u20091945\u2009mL (range: 1043 to 6816\u2009mL), LV<\/jats:styled-content> was 2198\u2009\u00b1\u20091139\u2009mL (1005 to 4116\u2009mL), and the total organ volume (TV<\/jats:styled-content>\u2009=\u2009KV<\/jats:styled-content>\u2009+\u2009LV<\/jats:styled-content>) was 4985\u2009\u00b1\u20091815\u2009mL (2320 to 8912\u2009mL). In the patient with the largest TV<\/jats:styled-content> from group 1 (KV<\/jats:styled-content> of 6816\u2009mL, TV<\/jats:styled-content> of 8912\u2009mL, and TV<\/jats:styled-content>\/BMI<\/jats:styled-content> ratio of 426, PD<\/jats:styled-content> was stopped due to dialysate leakage. However, dialysate leakage did not occur in the other 14 patients (TV<\/jats:styled-content>\u2009\u2266\u20097963\u2009mL and TV<\/jats:styled-content>\/BMI<\/jats:styled-content> ratio of 353 at the start of PD<\/jats:styled-content>). In group 2, KV<\/jats:styled-content> was 5822\u2009\u00b1\u20091597\u2009mL (3832 to 8862\u2009mL), LV<\/jats:styled-content> was 1776\u2009\u00b1\u2009519\u2009mL (1271 to 2671\u2009mL), and TV<\/jats:styled-content> was 7597\u2009\u00b1\u20091431\u2009mL (5505 to 10358) before TAE<\/jats:styled-content>. Leakage of dialysate did not occur with a mean infusion volume of 1530\u2009\u00b1\u2009370\u2009mL (1000\u2009mL to 2000\u2009mL), even after renomegaly and hepatomegaly progressed to the maximum TV<\/jats:styled-content>\/BMI<\/jats:styled-content> ratio of 359. Six patients from the two groups developed new abdominal hernias at 36\u2009\u00b1\u20095 months (6\u201355 months) after starting PD<\/jats:styled-content>. These findings suggest that performance of PD<\/jats:styled-content> may be limited by renomegaly and hepatomegaly in patients with PKD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/1744-9987.12272","type":"journal-article","created":{"date-parts":[[2015,1,22]],"date-time":"2015-01-22T07:40:55Z","timestamp":1421912455000},"page":"207-211","source":"Crossref","is-referenced-by-count":12,"title":["Peritoneal Dialysis is Limited by Kidney and Liver Volume in Autosomal Dominant Polycystic Kidney Disease"],"prefix":"10.1111","volume":"19","author":[{"given":"Satoshi","family":"Hamanoue","sequence":"first","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichi","family":"Hoshino","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo 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Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koki","family":"Mise","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Kawada","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Imafuku","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Hayami","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiichi","family":"Sumida","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikako","family":"Hiramatsu","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiko","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Sawa","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kennmei","family":"Takaichi","sequence":"additional","affiliation":[{"name":"Nephrology Center Toranomon Hospital Tokyo Japan"},{"name":"Okinaka Memorial Institute for Medical Research Toranomon Hospital Tokyo 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