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Diastolic <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>, also called <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> with preserved ejection fraction, refers to a clinical syndrome in which patients have symptoms and signs of <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content>, normal or near normal left ventricular (<jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content>) systolic function, and evidence of diastolic dysfunction manifested by abnormal <jats:styled-content style=\"fixed-case\">LV<\/jats:styled-content> filling and elevated filling pressure. Recent reports suggest that <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> with preserved ejection fraction is more common in hemodialysis patients than <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> with low ejection fraction. Diastolic <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> patients is a strong predictor of death. In this article, we review the information available in the literature on the pathogenesis, diagnosis, and potential treatment strategies of diastolic dysfunction or diastolic <jats:styled-content style=\"fixed-case\">HF<\/jats:styled-content> based on evidence obtained in the general population that is potentially applicable to <jats:styled-content style=\"fixed-case\">ESKD<\/jats:styled-content> patients.<\/jats:p>","DOI":"10.1111\/1744-9987.12301","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T10:17:22Z","timestamp":1430129842000},"page":"427-435","source":"Crossref","is-referenced-by-count":17,"title":["Left Ventricular Diastolic Dysfunction in End\u2010Stage Kidney Disease: Pathogenesis, Diagnosis, and Treatment"],"prefix":"10.1111","volume":"19","author":[{"given":"Tetsuya","family":"Ogawa","sequence":"first","affiliation":[{"name":"Department of Medicine Medical Center East and Kidney Center Tokyo Women's Medical University  Tokyo 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