{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T11:57:34Z","timestamp":1778155054493,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2016,3,17]],"date-time":"2016-03-17T00:00:00Z","timestamp":1458172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This cross\u2010sectional study aimed to determine the utility of ultrasonography with improved resolution using a high\u2010frequency probe for dialysis\u2010related carpal tunnel syndrome (CTS). This study targeted 125 hemodialysis patients at our hospital. A 12 MHz probe was placed on the carpal tunnel area to identify the median nerve. The compression rate of the nerve was calculated by measuring the smallest diameter of the compressed nerve and largest diameter of the unaffected part. To quantify CTS symptoms, we determined the presence of Tinel's sign, measured pinch strength, and used questionnaires to assess numbness and pain. The association of these clinical data with the compression rate was examined. Mean compression rate was 12.1\u2009\u00b1\u20091.1%. The compression rate cutoff value for those positive with Tinel's sign was 25%, (sensitivity and specificity were 0.80 and 0.91, respectively), and that for those with a history of CTS surgery was 25% (sensitivity and specificity were 0.67 and 0.89, respectively). Multiple regression analysis identified duration of dialysis, \u03b22\u2010microglobulin(\u03b22\u2010Mg) concentration, positivity for Tinel's sign, history of CTS surgery, and pinch strength as independent compression rate determinants. Notably, compression rates were significantly higher in patients with a \u22654\u2010year duration of dialysis and a \u03b22\u2010Mg level of 20\u2009mg\/L or more. The compression rate of the median nerve measured by an improved ultrasound device significantly correlated with clinical symptoms, medical history, and serological features associated with dialysis\u2010related CTS. Because ultrasonography is non\u2010invasive, the examination might be a simple method especially for early diagnosis of dialysis\u2010related CTS.<\/jats:p>","DOI":"10.1111\/1744-9987.12413","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T02:22:17Z","timestamp":1458354137000},"page":"483-491","source":"Crossref","is-referenced-by-count":5,"title":["Utility of Ultrasonography of the Median Nerve With a High\u2010Frequency Probe for the Diagnosis of Dialysis\u2010Related Carpal Tunnel Syndrome"],"prefix":"10.1111","volume":"20","author":[{"given":"Tadashi","family":"Yamazaki","sequence":"first","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naomi","family":"Kawahara","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Arai","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Oyoshi","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masami","family":"Oshima","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Koike","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Miyauchi","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokie","family":"Hayasaka","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Saito","sequence":"additional","affiliation":[{"name":"Hemodialysis Unit Moka Hospital  Tochigi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuichi","family":"Tsuruoka","sequence":"additional","affiliation":[{"name":"Department of Nephrology Nippon Medical School  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2006.00134.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g6437"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(85)91948-5"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198602273140920"},{"issue":"5","key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1159\/000362567","article-title":"Carpal tunnel surgery as proxy for dialysis\u2010related amyloidosis: results from the Japanese society for dialysis therapy","volume":"39","author":"Hoshino J","year":"2014","journal-title":"Am J Nephrol"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.11277"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu275"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon.12261"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-014-1929-z"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12031"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-006-1013-1"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000328959"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2012.01130.x"},{"issue":"4","key":"e_1_2_6_15_1","first-page":"231","article-title":"Ultrasonographic evaluation of the carpal tunnel syndrome in hemodialysis patients","volume":"44","author":"Ikegaya N","year":"1995","journal-title":"Clin Nephrol"},{"issue":"6","key":"e_1_2_6_16_1","first-page":"375","article-title":"Ultrasound changes in the wrist and hand in hemodialysis patients","volume":"48","author":"Lanteri M","year":"1997","journal-title":"Clin Nephrol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP57230"},{"issue":"4","key":"e_1_2_6_18_1","first-page":"233","article-title":"Hemodialysis\u2010related lesions of the hand","volume":"62","author":"Asencio G","year":"1995","journal-title":"Rev Rhum Engl Ed"},{"key":"e_1_2_6_19_1","first-page":"99","article-title":"Sensitivity and specificity of median nerve ultrasonography in diagnosis of carpal tunnel syndrome","volume":"5","author":"Yazdchi M","year":"2012","journal-title":"Int J Gen Med"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.32.11.1987"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2009.28.6.727"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.5535\/arm.2012.36.1.72"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2012.01143.x"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1744-9987.12413","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.12413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T09:11:10Z","timestamp":1695978670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.12413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,17]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1111\/1744-9987.12413"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.12413","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,17]]}}}