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When the mean processed volume for SePE was 1.2 plasma volumes, the mean percent reduction was 50.7% for desmoglein 1, 48.9% for desmoglein 3, 50.3% for IgG, 29.8% for IgA, 1.9% for IgM, and 17.6% for fibrinogen. In one case, the percent reduction after four sessions of SePE within eight days was 87.0% for desmoglein 1, 85.1% for desmoglein 3, 76.6% for IgG, 53.5% for IgA, 7.9% for IgM, 41.6% for fibrinogen, and 31.4% for factor XIII. SePE can effectively remove pemphigus autoantibodies and retain coagulation factors, e.g. factor XIII and fibrinogen. In severe cases, SePE can be useful and safe for induction therapy.<\/jats:p>","DOI":"10.1111\/1744-9987.12555","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T10:45:13Z","timestamp":1498733113000},"page":"226-231","source":"Crossref","is-referenced-by-count":8,"title":["Selective Plasma Exchange for the Removal of Pemphigus Autoantibodies, Fibrinogen, and Factor XIII in Pemphigus Vulgaris"],"prefix":"10.1111","volume":"21","author":[{"given":"Satoko","family":"Miyamoto","sequence":"first","affiliation":[{"name":"Medical Engineering Center Medical Hospital of Tokyo Medical and Dental University  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Ohkubo","sequence":"additional","affiliation":[{"name":"Medical Engineering Center Medical Hospital of Tokyo Medical and Dental University  Tokyo 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