{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:05:16Z","timestamp":1789193116957,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,7,15]],"date-time":"2018-07-15T00:00:00Z","timestamp":1531612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Therapeutic plasma exchange is used in treating different immunological and non\u2010immunological diseases. We analyzed the outcome of 308 patients treated by 1783 membrane plasma exchange sessions from January 2011 until January 2017 at Cairo University Hospital. Thrombotic microangiopathies were the commonest indication [73 (23.7%) patients] with response in 63\/73 patients (86.3%), followed by systemic vasculitis with pulmonary\u2010renal involvement [40(13%) patients] with recovery in 32\/40 patients (80.0%), Guillain\u2010Barr\u00e9 syndrome [39(12.7%) patients] with recovery in 30\/39 patients (76.9%), myasthenia gravis [31(10.1%) patients] with response in 26\/31 patients (83.9%), and catastrophic antiphospholipid syndrome [28(9.1%) patients] with recovery in only 6\/28 patients (21.4%). Complications included hypotension [276\/1783 (15.5%) sessions], hypocalcemia [26\/308 (8.5%) patients], and 37\/308 (12%) patients died. Sepsis caused mortality in 29\/37 (78.4%) of patients. In conclusion, our therapeutic plasma exchange experience shows a favorable outcome for thrombotic microangiopathies, systemic vasculitis, myasthenia gravis, and Guillain\u2010Barr\u00e9 syndrome. Sepsis was the leading mortality cause.<\/jats:p>","DOI":"10.1111\/1744-9987.12710","type":"journal-article","created":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T03:30:21Z","timestamp":1531711821000},"page":"666-673","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Therapeutic Plasma Exchange Outcomes in Cairo University Hospitals: 6 Years Experience"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0170-4205","authenticated-orcid":false,"given":"Mohamed","family":"Momtaz","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Nephrology Unit Cairo University Hospital  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Fayed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Nephrology Unit Cairo University Hospital  Cairo 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