{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T01:36:56Z","timestamp":1783215416523,"version":"3.54.6"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T00:00:00Z","timestamp":1586908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Renal replacement treatment has not been generalized to the elderly for different reasons. The main objective of the present cohort study is to compare survival in patients older than 80\u2009years with chronic kidney disease stage 5 on renal replacement treatment with those on conservative treatment. The use of healthcare resources is compared too. A Cox proportional hazards regression analysis was run with the outcome variable death during the follow\u2010up period. The independent variables were treatment type, age, gender, smoking habit, serum albumin, hemoglobin, Charlson Index, diabetes mellitus, arterial hypertension, ischemic cardiopathy, and neoplasm. For outcome variable \u201cdeath,\u201d renal replacement treatment obtained a hazard ratio of 0.273 (<jats:italic>P<\/jats:italic> .006, CI95% 0.108\u20100.686) vs conservative treatment. In conclusion, patients older than 80\u2009years with chronic kidney disease stage 5 on renal replacement treatment presented a lower mortality risk than those receiving conservative treatment. Comorbidity and age are both associated with mortality, but do not cancel out the survival advantage. In healthcare resources, the renal replacement treatment group made greater use of tests, medical visits and consumption of hospital dispensing drugs, but there were no differences with respect to the days of hospital admission or assistance in home hospitalization.<\/jats:p>","DOI":"10.1111\/1744-9987.13493","type":"journal-article","created":{"date-parts":[[2020,4,7]],"date-time":"2020-04-07T13:26:30Z","timestamp":1586265990000},"page":"24-32","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Cohort study with patients older than 80\u2009years with stage 5 chronic kidney failure on hemodialysis vs conservative treatment: Survival outcomes and use of healthcare resources"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2601-3427","authenticated-orcid":false,"given":"Alicia","family":"Garc\u00eda Testal","sequence":"first","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Garc\u00eda Maset","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Forn\u00e9s Ferrer","sequence":"additional","affiliation":[{"name":"Biostatistics Unit Instituto de Investigaci\u00f3n Sanitaria La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio J.","family":"Ca\u00f1ada Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Biostatistics Unit Instituto de Investigaci\u00f3n Sanitaria La Fe  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Fern\u00e1ndez Fandos","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inmaculada S.","family":"Rico Salvador","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Royo Maicas","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanesa","family":"Carretero L\u00f3pez","sequence":"additional","affiliation":[{"name":"Research Unit Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Villal\u00f3n Coca","sequence":"additional","affiliation":[{"name":"Business Control Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose E.","family":"Fern\u00e1ndez Najera","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caterina","family":"Benedito Carrera","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pau","family":"Olag\u00fce D\u00edaz","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Torregrosa De Juan","sequence":"additional","affiliation":[{"name":"Nephrology Service Hospital de Manises  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,15]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"1","article-title":"Epidemiolog\u00eda de la insuficiencia renal terminal en tratamiento sustitutivo con di\u00e1lisis en el anciano","volume":"28","author":"Barrio V","year":"1998","journal-title":"Nefrolog\u00eda"},{"issue":"1","key":"e_1_2_8_3_1","first-page":"39","article-title":"Hemodi\u00e1lisis en pacientes de edad avanzada. 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