{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:22:39Z","timestamp":1762543359410,"version":"3.40.5"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T00:00:00Z","timestamp":1615852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Carotid intima\u2010media thickness (CIMT) is an early marker of atherosclerosis and is increased in peritoneal dialysis (PD) patients. Association of CIMT with cardiovascular disease (CVD) or mortality is less clear. Fibroblast growth factor\u201023 (FGF\u201023) is a hormone associated with vascular calcification, atherosclerosis, and mortality in the hemodialysis population. We investigated whether baseline CIMT and FGF\u201023 are associated with CVD and mortality in PD patients. Fifty\u2010five PD patients were included. CVD was defined as ischemic heart disease, stroke, or peripheral artery disease. Intact FGF\u201023 was measured in plasma. CIMT was measured by ultrasonography. Twenty\u2010one patients developed CVD and 12 died over 47.1\u2009\u00b1\u200933.8\u00a0months. Patients with CVD were older (55.9\u2009\u00b1\u200910.5 vs. 42.5\u2009\u00b1\u200912.9\u2009years, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), had lower albumin (3.8\u2009\u00b1\u20090.5 vs. 4.2\u2009\u00b1\u20090.3\u00a0g\/dL, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) and higher CIMT (0.87\u2009\u00b1\u20090.22 vs. 0.61\u2009\u00b1\u20090.11\u2009mm, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Patients with mortality were also older (53.5\u2009\u00b1\u200911.5 vs. 45.8\u2009\u00b1\u200913.8\u2009years, <jats:italic>P<\/jats:italic>\u00a0=\u00a0.05), had lower albumin (3.7\u2009\u00b1\u20090.6 vs. 4.1\u2009\u00b1\u20090.3\u00a0g\/dL, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01), higher CRP (15.0\u2009\u00b1\u20098.5 vs. 7.6\u2009\u00b1\u20098.4\u00a0mg\/L, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01) and CIMT (0.9\u2009\u00b1\u20090.3 vs. 0.6\u2009\u00b1\u20090.1\u2009mm, <jats:italic>P<\/jats:italic>\u2009&lt;\u2009.01). Albumin and CIMT were associated with CVD and CIMT\u2009&gt;\u2009\u20090.75 mm was associated with cardiovascular mortality. FGF\u201023 did not show any correlations. CIMT at baseline is associated with CVD and mortality in PD patients.<\/jats:p>","DOI":"10.1111\/1744-9987.13629","type":"journal-article","created":{"date-parts":[[2021,1,29]],"date-time":"2021-01-29T07:28:01Z","timestamp":1611905281000},"page":"962-969","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Baseline carotid intima\u2010media thickness is associated with cardiovascular morbidity and mortality in peritoneal dialysis patients"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5685-115X","authenticated-orcid":false,"given":"Ebru","family":"Asicioglu","sequence":"first","affiliation":[{"name":"Department of Nephrology Marmara University Pendik Teaching Hospital  Istanbul Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arzu","family":"Velioglu","sequence":"additional","affiliation":[{"name":"Department of Nephrology Marmara University Pendik Teaching 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