{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T04:16:44Z","timestamp":1775017004279,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T00:00:00Z","timestamp":1616457600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Pregnancy\u2010related acute kidney injury (PRAKI) particularly on top of preeclampsia (PE) represents a major cause of maternal and fetal morbidity and mortality. Reliable diagnostic tools are needed to further evaluate the diagnosis and prognosis of PRAKI. Our objective was to study the diagnostic and prognostic value of angiogenic markers (e.g., stromal cell\u2010derived factor 1 (SDF\u20101), vascular endothelial growth factor (VEGF), alarmins as uric acid) in women with PE and PRAKI. This prospective study included three groups; PRAKI, PE patients, and healthy controls that were compared regarding serum levels of the studied markers correlated to renal, maternal, and fetal outcomes. SDF\u20101, VEGF, and uric acid levels were significantly different between the three included groups and predicted PRAKI diagnosis. Patients with hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome exhibited the highest titers of SDF\u20101 and VEGF. A positive correlation was found between SDF\u20101 and renal recovery. Conclusively, serum assays of SDF\u20101, VEGF, and uric acid may add a diagnostic value in PRAKI and PE.<\/jats:p>","DOI":"10.1111\/1744-9987.13633","type":"journal-article","created":{"date-parts":[[2021,2,6]],"date-time":"2021-02-06T00:50:15Z","timestamp":1612572615000},"page":"306-315","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Angiogenic markers predict kidney injury and obstetric complications in women with preeclampsia and pregnancy\u2010related acute kidney injury"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0770-8023","authenticated-orcid":false,"given":"Rasha Samir","family":"Shemies","sequence":"first","affiliation":[{"name":"Mansoura Nephrology and Dialysis Unit Mansoura University  Mansoura Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamer Zaki","family":"Gaber","sequence":"additional","affiliation":[{"name":"Mansoura Nephrology 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