{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T16:38:06Z","timestamp":1764175086677,"version":"3.40.5"},"reference-count":47,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T00:00:00Z","timestamp":1632355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Our aim was to evaluate biochemical markers in plasma (NGAL, CysC) and urine (NGAL, KIM\u20101) in children's early onset of acute kidney injury after congenital heart defect surgery using cardiopulmonary bypass. This study prospectively included 100 children with congenital heart defects who developed AKI. Patients with acute kidney injury had significantly higher CysC levels 6 and 12\u2009h after cardiac surgery and plasma NGAL levels 2 and 6\u00a0h after cardiac surgery. The best predictive properties for the development of acute kidney injury are the combination (+CysCpl or +NGALu) after 12\u2009h and a combination (+CysCpl and +NGALu) 6 and 24\u2009h after cardiac surgery. We showed that plasma CysC and urinary NGAL could reliably predict the development of acute kidney injury. Measurement of early biochemical markers in plasma and urine, individually and combination, may predict the development of cardiac surgery\u2010associated acute kidney injury in children.<\/jats:p>","DOI":"10.1111\/1744-9987.13736","type":"journal-article","created":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T20:07:56Z","timestamp":1632514076000},"page":"583-593","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Early biochemical markers in the assessment of acute kidney injury in children after cardiac surgery"],"prefix":"10.1111","volume":"26","author":[{"given":"Slobodan","family":"Gali\u0107","sequence":"first","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danko","family":"Milo\u0161evi\u0107","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"},{"name":"School of Medicine  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Filipovi\u0107\u2010Gr\u010di\u0107","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"},{"name":"School of Medicine  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dunja","family":"Rogi\u0107","sequence":"additional","affiliation":[{"name":"School of Medicine  Zagreb Croatia"},{"name":"Clinical Institute for Laboratory Diagnostics University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u017deljka","family":"Vogrinc","sequence":"additional","affiliation":[{"name":"Clinical Institute for Laboratory Diagnostics University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vi\u0161nja","family":"Ivan\u010dan","sequence":"additional","affiliation":[{"name":"Clinic of Anesthesiology Resuscitation and Intensive Care University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toni","family":"Mati\u0107","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filip","family":"Rubi\u0107","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miran","family":"Cvitkovi\u0107","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matija","family":"Bako\u0161","sequence":"additional","affiliation":[{"name":"Pediatric Clinic University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6264-6809","authenticated-orcid":false,"given":"Vedran","family":"Premu\u017ei\u0107","sequence":"additional","affiliation":[{"name":"School of Medicine  Zagreb Croatia"},{"name":"Department of Nephrology, Hypertension, Dialysis, and Transplantation University Hospital Center Zagreb  Zagreb Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,9,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9784.179635"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ppedcard.2016.01.011"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2018.03.007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.10.046"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31821201d3"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2011.06.021"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-013-2495-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.06.054"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft510"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05150512"},{"key":"e_1_2_7_12_1","article-title":"Cystatin C and neutrophil gelatinase\u2010associated lipocalin: biomarkers for acute kidney injury after congenital heart surgery","volume":"143","author":"Seitz S","year":"2013","journal-title":"Swiss Med Wkly"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2013.07.008"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2011.269647"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010111163"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010121302"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.132194"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.02.389"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-017-0539-0"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezv199"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.48.113006.094615"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2012.01.014"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152811796117735"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-012-0563-6"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.017"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc6192"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.12.057"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.11.007"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002231"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008030287"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.54"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.02040310"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e318238b43c"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/chd.12253"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)74811-X"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04010907"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.5114\/aoms.2012.28552"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000034"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04730513"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.051"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.10.854"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2011-0814"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00433.x"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.24267"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084131"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-014-2989-y"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.09.066"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5002715"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13736","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.13736","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T16:42:46Z","timestamp":1692981766000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.13736"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,23]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/1744-9987.13736"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.13736","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"type":"print","value":"1744-9979"},{"type":"electronic","value":"1744-9987"}],"subject":[],"published":{"date-parts":[[2021,9,23]]},"assertion":[{"value":"2021-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}