{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T17:56:58Z","timestamp":1771523818593,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Xerostomia and hyposalivation are highly prevalent in hemodialysis (HD) patients and this is effective in increased fluid intake. The aim of this study is to determine the demographic and clinical risk factors associated with high interdialytic weight gain (IDWG) in nondiabetic HD patients. In total, 52 eligible HD patients were recruited in this cross\u2010sectional study. Patients were divided into two groups according to % IDWG: Group 1: High IDWG (\u22653%) and Group 2: normal IDWG (&lt;3%). Plasma osmolarity (POsm), unstimulated salivary flow rate (USFR), xerostomia inventory (XI), and dialysis thirst inventory (DTI) were evaluated. The mean age of the patients was 53.7\u2009\u00b1\u200915.7\u2009years. The prevalence of xerostomia was 53.8%, and hyposalivation was in 40.3% in the patients. High IDWG was positively correlated with XI and DTI while it was negatively correlated with POsm and USFR. The area under the receiver\u2010operating characteristics curve for POsm for high IDWG was 0.661, with sensitivity of 63.8% and specificity of 72.7% for a cut\u2010off point of 297.4\u00a0mOsm\/L. Logistic regression analysis showed that advanced age odds ratio (OR: 1.215, <jats:italic>p<\/jats:italic>\u00a0=\u20090.019), pill burden (OR: 1.162, <jats:italic>p<\/jats:italic>\u00a0=\u20090.031), C\u2010reactive protein (CRP; OR: 1.308, <jats:italic>p<\/jats:italic>\u00a0=\u20090.042), and low POsm (OR: 0.768, <jats:italic>p<\/jats:italic>\u00a0=\u20090.046) were independently related to high IDWG. The prevalence of xerostomia and thirst was higher in HD patients with high IDWG compared to the normal IDWG group. Age, CRP, low POsm, and pill burden were independently associated with high IDWG.<\/jats:p>","DOI":"10.1111\/1744-9987.13738","type":"journal-article","created":{"date-parts":[[2021,9,17]],"date-time":"2021-09-17T11:04:08Z","timestamp":1631876648000},"page":"613-623","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of demographic and clinical risk factors for high interdialytic weight gain"],"prefix":"10.1111","volume":"26","author":[{"given":"Sevcihan","family":"G\u00fcnen Y\u0131lmaz","sequence":"first","affiliation":[{"name":"Department of Maxillofacial Radiology, Faculty of Dentistry Akdeniz University  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4599-3299","authenticated-orcid":false,"given":"Fatih","family":"Y\u0131lmaz","sequence":"additional","affiliation":[{"name":"Department of Nephrology Antalya Atat\u00fcrk State Hospital  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00636.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/5972930"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2016.08.030"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2012.346"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.383"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000362743"},{"issue":"2","key":"e_1_2_7_8_1","first-page":"e185","article-title":"Risk factors associated with xerostomia in haemodialysis patients","volume":"22","author":"Lopez\u2010Pintor RM","year":"2017","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfh675"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2011.218"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.12334"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-015-0110-9"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.09314.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345920710070301"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V451205"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2013-0669"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00933.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079-2104(99)70035-1"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/sdi.12821"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/bdj.2007.47"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.5414\/cnp67025"},{"key":"e_1_2_7_22_1","first-page":"e1340","article-title":"Evaluation of changes in salivary composition in renal failure patients before and after hemodialysis","volume":"9","author":"Khanum N","year":"2017","journal-title":"J Clin Exp Dent"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000058394"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-013-0576-y"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02993714"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.1999.tb00093.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00908-9"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200109000-00016"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2013.05.002"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2010.00420.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-020-02401-5"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1997.tb00928.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-019-1573-x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-020-02461-7"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.03.028"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1159\/000504194"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1258\/000456307781646030"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1159\/000168421"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13374"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.09050815"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.05440611"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.22294"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13738","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.13738","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T16:43:02Z","timestamp":1692981782000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.13738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1111\/1744-9987.13738"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.13738","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"2021-03-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}