{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:28:34Z","timestamp":1747182514753,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T00:00:00Z","timestamp":1642377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We investigated whether N\u2010terminal and C\u2010terminal products of expressed in renal cell carcinoma\/mesothelin (N\u2010ERC and C\u2010ERC) in peritoneal effluent can predict peritoneal permeability in patients undergoing peritoneal dialysis (PD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010seven peritoneal effluent samples were obtained from 26 PD patients. High transport status was determined by the peritoneal equilibration test as a dialysate\/plasma ratio of creatinine (D\/P Cr)\u2009\u2265\u20090.81. Effluent cancer antigen 125 (CA125) was used as a reference.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Effluent N\u2010ERC concentration was better correlated with D\/P Cr than effluent C\u2010ERC or CA125 concentration. In multivariate analyses, effluent N\u2010ERC and C\u2010ERC, but not CA125, were significant predictors of high transport status after adjusting for age, PD duration, and residual renal Kt\/V. ROC analysis showed that effluent N\u2010ERC was the best predictor of high transport status among those three biomarkers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Effluent N\u2010ERC predicts increased peritoneal permeability in patients undergoing PD.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.13786","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T08:24:40Z","timestamp":1640679880000},"page":"1014-1022","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effluent N\u2010terminal expressed in renal cell carcinoma\/mesothelin predicts increased peritoneal permeability in patients undergoing peritoneal dialysis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4568-9839","authenticated-orcid":false,"given":"Mayumi","family":"Idei","sequence":"first","affiliation":[{"name":"Department of Clinical Laboratory Medicine Juntendo University Graduate School of Medicine  Tokyo Japan"},{"name":"Medical Technology Innovation Center Juntendo University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oncology Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8082-8945","authenticated-orcid":false,"given":"Mototsugu","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Clinical and Translational Research Center Niigata University Medical and Dental Hospital  Niigata Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junichiro","family":"Nakata","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miwa","family":"Isshiki","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine Juntendo University Graduate School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Okio","family":"Hino","sequence":"additional","affiliation":[{"name":"Department of Pathology and Oncology Juntendo University Faculty of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Miida","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Medicine Juntendo University Graduate School of Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,17]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V113556"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.059002754.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0896860819894066"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.08.028"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009060635"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016010112"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2013.00074"},{"issue":"2","key":"e_1_2_8_9_1","first-page":"S175","article-title":"Searching for the reasons for drop\u2010out from peritoneal dialysis: a nationwide survey in Japan","volume":"23","author":"Kawaguchi Y","year":"2003","journal-title":"Perit Dial Int"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.13509"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.01.031"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2013.99"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009070694"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.V132470"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2017.00018"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2011.93"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/089686088700700306"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.186"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/089686080302300204"},{"key":"e_1_2_8_20_1","first-page":"131","article-title":"High\u2010transport membrane is a risk factor for encapsulating peritoneal sclerosis developing after long\u2010term continuous ambulatory peritoneal dialysis treatment","volume":"18","author":"Yamamoto R","year":"2002","journal-title":"Adv Perit Dial"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/089686089501500420"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.125"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/17.8.1480"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0896860820982218"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2009.00022"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl566"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2006.02024.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2006.00246.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-1613"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2016.08.009"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.297"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2014090939"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13786","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.13786","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13786","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T17:05:13Z","timestamp":1692637513000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.13786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,17]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/1744-9987.13786"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.13786","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"type":"print","value":"1744-9979"},{"type":"electronic","value":"1744-9987"}],"subject":[],"published":{"date-parts":[[2022,1,17]]},"assertion":[{"value":"2021-08-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}