{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T10:30:59Z","timestamp":1781346659046,"version":"3.54.1"},"reference-count":39,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,5,28]],"date-time":"2022-05-28T00:00:00Z","timestamp":1653696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cryoglobulinemia is defined as the presence of an abnormal immunoglobulin that may be responsible for vasculitis of small\u2010caliber vessels. Apheresis can be used in order to temporarily eliminate circulating cryoglobulins. The aim of this study was to assess the effectiveness of apheresis (double\u2010filtration plasmapheresis\u2010DFPP\u2010) in symptomatic and\/or severe cryoglobulinemias.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Four male patients presenting cryoglobulinemic vasculitis and who received DFPP sessions were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Their mean age was 57\u2009\u00b1\u200915\u2009years. One patient had hepatitis\u2010C virus (HCV)\u2010related cryoglobulinemia and the other three patients were carriers of an IgM Kappa monoclonal gammopathy. Mean duration of follow\u2010up was 15\u2009\u00b1\u20092\u00a0months. DFPP allowed healing of ulcerative skin lesions in the first patient and remission of nephrotic syndrome in the other patients after a median of 6(5\u201310) sessions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>DFPP can be used safely in cryoglobulinemic\u2010vasculitis and can be considered early to achieve a faster and sustained clinical\u2010biological response.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.13885","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T11:20:15Z","timestamp":1652872815000},"page":"159-169","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Cryoglobulinemia and double\u2010filtration plasmapheresis: Personal experience and literature review"],"prefix":"10.1111","volume":"27","author":[{"given":"Hamza","family":"Naciri Bennani","sequence":"first","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augustin Twite","family":"Banza","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Terrec","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Noble","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"},{"name":"Grenoble Alpes University  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Jouve","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"},{"name":"Grenoble Alpes University  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Motte","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Malvezzi","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5130-7286","authenticated-orcid":false,"given":"Lionel","family":"Rostaing","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Hemodialysis, Apheresis, and Kidney Transplantation Grenoble University Hospital  Grenoble France"},{"name":"Grenoble Alpes University  Grenoble France"},{"name":"Ramathibodi Hospital Mahidol University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,28]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90852-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nephro.2018.02.003"},{"key":"e_1_2_10_4_1","first-page":"52","article-title":"Hyperproteinemia associated with multiple myeloma. With report of a case in which an extraordinary hyperproteinemia was associated with thrombosis of the retinal veins and symptoms suggesting Raynaud's disease","author":"Wintrobe MM","year":"1933","journal-title":"Bull John Hopkins Hosp"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-194710000-00009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2496467"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.4084\/MJHID.2017.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196009222631202"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21705"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21257"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.7117"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.5461-20"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12556"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002480-199905000-00024"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1159\/000183849"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410100514"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-0968.1999.00196.x"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-9987.2011.01004.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2018.06.005"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2013.8700"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20166"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.20222"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.21414"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(84)80031-1"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-007-0462-y"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-0502(03)00055-7"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1590-8658(07)80027-2"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-010-0282-3"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756284820942617"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.3816\/CLM.2009.n.026"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-58-5-789"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.3816\/CLM.2009.n.027"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-44560"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019000725"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-11-055012"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05948.x"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-347690"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nephro.2019.07.264"},{"issue":"3","key":"e_1_2_10_39_1","first-page":"186","article-title":"Cutaneous ulcers with type I cryoglobulinemia treated with plasmapheresis","volume":"14","author":"Vila AT","year":"2004","journal-title":"Eur J Dermatol"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.4076\/1757-1626-2-7859"}],"container-title":["Therapeutic Apheresis and Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13885","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1744-9987.13885","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1744-9987.13885","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T20:57:29Z","timestamp":1692478649000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1744-9987.13885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,28]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1111\/1744-9987.13885"],"URL":"https:\/\/doi.org\/10.1111\/1744-9987.13885","archive":["Portico"],"relation":{},"ISSN":["1744-9979","1744-9987"],"issn-type":[{"value":"1744-9979","type":"print"},{"value":"1744-9987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,28]]},"assertion":[{"value":"2022-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}