{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T17:33:06Z","timestamp":1787938386806,"version":"build-2784847793"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We evaluated the effect of intradialytic concurrent (resistance\u2010endurance) training combined with melatonin (MEL) supplementation on functional capacity, muscle strength, postural balance, and quality of life (QoL) in hemodialysis (HD) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010three HD patients were randomized into three groups: Exercise (EX)\u2010MEL (<jats:italic>n<\/jats:italic>\u00a0=\u200911); EX\u2010Placebo (PLA) (<jats:italic>n<\/jats:italic>\u00a0=\u200911) and Control (C)\u2010PLA (<jats:italic>n<\/jats:italic>\u00a0=\u200911). Participants included in the EX\u2010MEL and EX\u2010PLA groups were submitted to concurrent training for 12\u2009weeks.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>EX\u2010MEL and EX\u2010PLA improved functional capacity, muscle strength, QoL, and postural balance parameters in eyes open and eyes closed conditions. Parameters of postural balance in the dual task condition were improved only in EX\u2010MEL. EX\u2010MEL induced better results in some domains of QoL compared with EX\u2010PLA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Intradialytic concurrent training induced beneficial effects on physical function, muscle strength, postural balance, and QoL in HD patients. MEL supplementation combined with intradialytic exercise lead to better improvements in postural balance and QoL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.13964","type":"journal-article","created":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T13:14:11Z","timestamp":1672319651000},"page":"669-681","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of intradialytic exercise in combination with melatonin supplementation on functional capacity, postural balance, and quality of life in hemodialysis patients"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3019-2042","authenticated-orcid":false,"given":"Houssem","family":"Marzougui","sequence":"first","affiliation":[{"name":"Research Laboratory Molecular Bases of Human Pathology LR19ES13, Faculty of Medicine University of Sfax  Sfax Tunisia"},{"name":"High Institute of Sport and Physical Education of Sfax 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