{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:29:06Z","timestamp":1747182546387,"version":"3.40.5"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T00:00:00Z","timestamp":1687651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Coagulation system dysfunction is associated with adverse outcomes of peritoneal dialysis (PD) and bacterial infection. We investigated the association between coagulation system and treatment failure of peritoneal dialysis\u2010related peritonitis (PDRP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected records of patients aged \u226518\u2009years with PDRP. PDRP episodes were divided into: shortened activated partial thromboplastin time (APTT) group and prolonged APTT group, low D\u2010dimer (DD) group and high DD group. The baseline characteristics of the groups were collected and compared. The association between APTT, DD and treatment failure of PDRP was analyzed using logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty episodes of treatment failure were observed in 110 episodes of PDRP in our study. After adjusting for variables, prolonged APTT (OR\u2009=\u20091.166 [1.049\u20131.296], <jats:italic>p<\/jats:italic>\u2009=\u20090.004) or high level of DD (OR\u2009=\u20091.374 [1.057\u20131.787], <jats:italic>p<\/jats:italic>\u2009=\u20090.017) was associated with treatment failure of PDRP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prolonged baseline APTT or high level of DD increased the risk of treatment failure of PDRP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.14027","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T04:09:45Z","timestamp":1687752585000},"page":"918-925","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Higher D\u2010dimer and activated partial thromboplastin time are poor prognostic factors in patients with peritoneal dialysis\u2010related peritonitis"],"prefix":"10.1111","volume":"27","author":[{"given":"Ya\u2010Juan","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Nephrology, The Sixth Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Ping","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The Sixth Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The Sixth Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia\u2010Fan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The Sixth Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6137-2674","authenticated-orcid":false,"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nephrology, The Sixth Affiliated Hospital Sun Yat\u2010sen University  Guangzhou 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