{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:55:50Z","timestamp":1773662150885,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Treatment with erythropoietin\u2010stimulating agents (ESAs) is widely used in anemia of chronic kidney disease (CKD). Acquired ESA resistance is an important problem. The aim of this study is to examine the bone marrow findings in hemodialysis patients with ESA\u2010resistant anemia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The data of 210 patients with acquired ESA resistance were reviewed retrospectively. The patients were divided into groups according to having diagnosis of dysplasia and hematological disease, and survival analysis was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 26 patients were included in the study. While dysplasia was present in 10 (38.5%) patients, five of them were diagnosed hematologically. When survival analysis was performed between those with and without a hematological diagnosis, a difference in survival was observed against the group with the diagnosis (24.4 vs. 72\u2009months, <jats:italic>p<\/jats:italic>\u2009=\u20090.045).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Unresponsiveness to ESA treatment in CKD patients or a decrease in one of the other cell lines along with hemoglobin, it would be appropriate to perform early bone marrow examination.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.14086","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T13:01:34Z","timestamp":1700571694000},"page":"218-224","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of bone marrow findings in hemodialysis patients with erythropoietin\u2010resistant anemia"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7447-9187","authenticated-orcid":false,"given":"Mehmet","family":"Yilmaz","sequence":"first","affiliation":[{"name":"Department of \u0130nternal Medicine Yunus Emre State Hospital  Eski\u015fehir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9178-2850","authenticated-orcid":false,"given":"Volkan","family":"Karaku\u015f","sequence":"additional","affiliation":[{"name":"Department of Internal Diseases, Division of Hematology University of Health Sciences, Antalya Training &amp; Research Hospital  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0466-7294","authenticated-orcid":false,"given":"Egemen","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Physiology Mugla Sitki Kocman University Faculty of Medicine  Mugla Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4777-4025","authenticated-orcid":false,"given":"Nevruz","family":"\u0130lhanl\u0131","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Medical Informatics Akdeniz University Faculty of Medicine  Antalya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8412-1584","authenticated-orcid":false,"given":"B\u00fclent","family":"Huddam","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine Mugla S\u0131tk\u0131 Ko\u00e7man University  Mugla Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-158-11-201306040-00007"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3329\/jemc.v4i1.18069"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2013.06.002"},{"key":"e_1_2_7_5_1","first-page":"973","volume-title":"Comprehensive clinical nephrology","author":"Feehally J","year":"2019"},{"key":"e_1_2_7_6_1","first-page":"1102","volume-title":"Oxford textbook of clinical nephrology","author":"Turner N","year":"2016"},{"key":"e_1_2_7_7_1","unstructured":"Lerma EV. Anemia and choronic kidney disease. In: Lerma EV Rosner MH Perazella MA editors. Current diagnosis & treatment nephrology & hypertension. 2nd ed. New York: McGraw Hill Medical Books; 2018. p.215\u2010221."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21527"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01524-6"},{"key":"e_1_2_7_10_1","unstructured":"KDIGO.Kidney Disease: Improving Global Outcomes clinical practice guideline for anemia in choronic kidney disease. 2012 Report. 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