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Vascular calcification (VC) is associated with increased morbidity and mortality and VC risk is higher in patients with CKD than in healthy individuals. Calcification inhibitors, compounds that inhibit VC, were discovered as a result of efforts to explain why some patients are spared. It was found that certain proteins (e.g., fetuin\u2010A, osteopontin, osteoprotegerin, bone morphogenetic protein\u20107) inhibit calcification in dialysis patients. In this narrative review, we provide an overview of known calcification inhibitors, describe the relevant regulatory mechanisms, and discuss their relation to VC development in PD patients.<\/jats:p>","DOI":"10.1111\/1744-9987.14091","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T06:56:58Z","timestamp":1701154618000},"page":"169-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Vascular calcification inhibitors and cardiovascular events in peritoneal dialysis patients"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1167-3628","authenticated-orcid":false,"given":"Refik","family":"Olmaz","sequence":"first","affiliation":[{"name":"Department of Nephrology Mersin City Hospital Mersin Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2617-2372","authenticated-orcid":false,"given":"Tamer","family":"Selen","sequence":"additional","affiliation":[{"name":"Department of Nephrology Duzce Ataturk State Hospital Duzce Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1861-5452","authenticated-orcid":false,"given":"Ozkan","family":"Gungor","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine Kahramanmaras S\u00fctc\u00fc Imam University Kahramanmaras Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2010.00186"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000488696"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2021.1918558"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.14001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2012.00037"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0202203"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000516285"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/2175-8239-jbn-2020-0040"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi236"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01926946"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00163.2014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharma.2009.04.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg414"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2004.07.022"},{"key":"e_1_2_7_16_1","unstructured":"Kidney Int Suppl Kidney Disease: Improving Global Outcomes (KDIGO) CKD\u2010MBD Update Work Group. 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