{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:26:37Z","timestamp":1747182397425,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aims to examine the relationship between fluid overload, Vascular Endothelial Growth Factor C (VEGF\u2010C), plasma Angiotensinogen (pAGT), and echocardiography findings in hemodialysis patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center, cross\u2010sectional study. Patients were divided into two groups according to mid\u2010week inter\u2010dialytic weight gain (mIDWG): (1) mIDWG \u22643% and (2) mIDW &gt;3%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 55 patients were enrolled in this study. While the mean pAGT and left ventricular mass index were significantly higher in patients with mIDWG &gt;3% compared to patients with mIDWG \u22643%, VEGF\u2010C was similar between groups. pAGT \u226576.8 mcg\/L, VEGF\u2010C \u2264175.5\u2009pg\/ML, and pAGT \/VEGF\u2010C \u22650.45 were significant cut\u2010offs for the prediction of left ventricular hypertrophy(LVH). Univariate logistic regression analysis revealed that these cut\u2010off values were significantly associated with LVH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Renin\u2010angiotensin\u2010aldosterone system activation may persist in hemodialysis patients with excessive IDWG. Additionally, pAGT and VEGF\u2010C could be risk factors for the development of LVH.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.14178","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T05:49:51Z","timestamp":1718776191000},"page":"904-911","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association of vascular endothelial growth factor\u2010C, plasma angiotensinogen and left ventricular hypertrophy in patients with hemodialysis"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5787-1048","authenticated-orcid":false,"given":"Haci Hasan","family":"Yeter","sequence":"first","affiliation":[{"name":"Department of Nephrology Hacettepe University Faculty of Medicine  Ankara 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