{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:38:35Z","timestamp":1789609115257,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,8,26]],"date-time":"2024-08-26T00:00:00Z","timestamp":1724630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Ther Apher Dial"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We aimed to evaluate the characteristics of the patients with a rheumatologic disease who underwent TPE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A single\u2010center, retrospective study was conducted between January 2016 and June 2023.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty patients with a median age of 51\u2009years received a median of 6 TPE sessions. Concurrently, immunosuppressive therapy was administered to 18 (90%) of them. During the follow\u2010up period, 9 patients (45%) died. Creatinine (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), C\u2010reactive protein (<jats:italic>p<\/jats:italic>\u2009=\u20090.001), sedimentation rate (<jats:italic>p<\/jats:italic>\u2009=\u20090.002), leukocyte (<jats:italic>p<\/jats:italic>\u2009=\u20090.003), thrombocyte (<jats:italic>p<\/jats:italic>\u2009=\u20090.003), and neutrophil (<jats:italic>p<\/jats:italic>\u2009=\u20090.003) counts was decreased after TPE. Similarly, in the ROC analysis of post TPE laboratory parameters, urea, creatinine, CRP, hemoglobin, platelets, and lymphocytes predicted mortality with areas under the curve values ranging from 0.747 to 0.869. In the Cox regression analysis for mortality, creatinine was predictive for mortality (<jats:italic>p<\/jats:italic>\u2009=\u20090.030), HR 1.59 (95% CI: 1.05\u20132.41).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In rheumatologic conditions, TPE is beneficial to fill the gap until the effects of immunosuppressants become apparent.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1744-9987.14199","type":"journal-article","created":{"date-parts":[[2024,8,27]],"date-time":"2024-08-27T05:03:57Z","timestamp":1724735037000},"page":"123-130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Therapeutic apheresis treatment in rheumatic diseases: Insights from a single\u2010center experience"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0156-011X","authenticated-orcid":false,"given":"Ezgi","family":"\u00c7imen 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